| Fri. | 20211022 | 10/22/2021 | 7:45 ET | Assumption | 0 | @ | LIU | 7 | | | NC | Box Score | |
| Sat. | 20211023 | 10/23/2021 | 2:00 ET | Post | 1 | @ | LIU | 6 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:30 ET | Aurora | 7 | @ | Arcadia | 0 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | Wentworth | 2 | @ | Castleton | 4 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | Stevenson | 4 | @ | Canton | 4 | OT | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | Marian | 1 | @ | Concordia (Minn.) | 4 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | Lebanon Valley | 4 | @ | Cortland | 6 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:15 ET | Wisconsin-River Falls | 2 | @ | Finlandia | 1 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | Lawrence | 5 | @ | Gustavus Adolphus | 2 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | Trine | 5 | @ | Hamline | 3 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | Brockport | 3 | @ | King's | 2 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | Saint Mary's | 3 | @ | (11) Lake Forest | 4 | OT | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:30 ET | Elmira | 4 | @ | Nazareth | 2 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 5:00 ET | (2) Geneseo | 6 | @ | Neumann | 3 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | St. Olaf | 2 | @ | Northland | 4 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | (6) Hobart | 3 | @ | Oswego | 1 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | Plymouth State | 3 | @ | Plattsburgh | 2 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | Southern New Hampshire | 4 | @ | Rivier | 5 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | (7) Endicott | 3 | @ | Salem State | 0 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | (8) Wisconsin-Stevens Point | 4 | @ | (13) St. Norbert | 3 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | Concordia (Wis.) | 4 | @ | St. Scholastica | 5 | OT | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 ET | New England College | 4 | @ | Suffolk | 0 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:00 CT | Bethel | 3 | @ | Wisconsin-Stout | 2 | OT | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 7:30 ET | Westfield State | 1 | @ | wnec | 3 | | | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 3:50 ET | Stonehill | 0 | @ | Curry | 1 | | Halloween Faceoff | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 6:50 ET | UMass Dartmouth | 3 | vs. | UMass Boston | 4 | | Halloween Faceoff | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 6:30 ET | Albertus Magnus | 2 | @ | Buffalo State | 3 | | Buffalo State Tournament | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 2:00 ET | Wilkes | 5 | vs. | Fredonia | 2 | | Buffalo State Tournament | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 6:50 ET | Assumption | 3 | vs. | Anna Maria | 3 | OT | Worcester City Cup | NC | Box Score | |
| Fri. | 20211029 | 10/29/2021 | 3:40 ET | Nichols | 6 | @ | Worcester State | 5 | | Worcester City Cup | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 3:30 ET | Aurora | 6 | @ | Arcadia | 3 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 4:00 ET | Stevenson | 4 | @ | Canton | 1 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 2:00 CT | Marian | 3 | @ | Concordia (Minn.) | 2 | OT | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 ET | Oswego | 4 | @ | Elmira | 5 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 4:00 ET | Wisconsin-River Falls | 4 | @ | Finlandia | 1 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 CT | Lawrence | 4 | @ | Gustavus Adolphus | 7 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 ET | Nazareth | 1 | @ | (2) Geneseo | 7 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 2:00 CT | Trine | 4 | @ | Hamline | 0 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 4:00 ET | Manhattanville | 2 | @ | (6) Hobart | 9 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 3:00 CT | Saint Mary's | 0 | @ | (11) Lake Forest | 3 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 ET | Morrisville | 4 | @ | Lebanon Valley | 5 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 4:00 ET | Brockport | 6 | @ | Neumann | 0 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 2:00 CT | St. Olaf | 1 | @ | Northland | 1 | OT | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 ET | Salve Regina | 2 | @ | (1) Norwich | 3 | OT | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 ET | Castleton | 1 | @ | Plattsburgh | 8 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 6:00 ET | (10) Babson | 2 | @ | Plymouth State | 1 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 6:45 ET | Johnson & Wales | 3 | @ | Post | 2 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 3:00 ET | Wentworth | 2 | @ | Skidmore | 0 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 ET | Rivier | 1 | @ | Saint Anselm | 4 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 CT | (4) Wisconsin-Eau Claire | 0 | @ | Saint John's | 1 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 CT | Wisconsin-Superior | 7 | @ | St. Scholastica | 0 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 5:00 ET | (5) Adrian | 2 | @ | (3) Utica | 3 | OT | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 CT | (13) St. Norbert | 5 | @ | (8) Wisconsin-Stevens Point | 3 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:00 CT | Concordia (Wis.) | 5 | @ | Wisconsin-Stout | 4 | | | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 4:00 ET | UMass Boston | 3 | @ | Curry | 5 | | Halloween Faceoff | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 1:00 ET | Stonehill | 0 | vs. | UMass Dartmouth | 8 | | Halloween Faceoff | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 3:30 ET | Fredonia | 4 | vs. | Albertus Magnus | 0 | | Buffalo State Tournament | NC | Box Score | |
| Sat. | 20211030 | 10/30/2021 | 7:30 ET | Wilkes | 2 | @ | Buffalo State | 1 | | Buffalo State Tournament | NC | Box Score | |
| Sun. | 20211031 | 10/31/2021 | 3:00 ET | (5) Adrian | 4 | @ | (3) Utica | 3 | | | NC | Box Score | |
| Sun. | 20211031 | 10/31/2021 | 3:40 ET | Worcester State | 3 | vs. | Assumption | 6 | | Worcester City Cup | NC | Box Score | |
| Sun. | 20211031 | 10/31/2021 | 6:50 ET | Nichols | 3 | vs. | Anna Maria | 3 | OT | Worcester City Cup | NC | Box Score | |
| Tue. | 20211102 | 11/2/2021 | 7:35 ET | Post | 1 | @ | Westfield State | 2 | | | NC | Box Score | |
| Wed. | 20211103 | 11/3/2021 | 7:00 ET | (2) Geneseo | 4 | @ | Morrisville | 1 | | | SU | Box Score | |
| Wed. | 20211103 | 11/3/2021 | 7:00 CT | Lawrence | 5 | @ | Saint Mary's | 1 | | | NC | Box Score | |
| Thu. | 20211104 | 11/4/2021 | 7:40 ET | Salem State | 2 | @ | Framingham State | 0 | | | MS | Box Score | |
| Thu. | 20211104 | 11/4/2021 | 6:40 ET | UMass Dartmouth | 6 | @ | Worcester State | 3 | | | MS | Box Score | |
| Thu. | 20211104 | 11/4/2021 | 5:30 CT | Concordia (Wis.) | 1 | @ | Aurora | 8 | | | NC | Box Score | |
| Thu. | 20211104 | 11/4/2021 | 7:35 ET | Rivier | 5 | @ | Westfield State | 4 | OT | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:40 ET | (14) University of New England | 7 | @ | Nichols | 2 | | | CO | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | (9) Endicott | 3 | @ | Salve Regina | 2 | | | CO | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Wentworth | 4 | @ | Suffolk | 4 | OT | Wentworth wins SO, 2-1 | CO | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Curry | 3 | @ | wnec | 1 | | | CO | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 6:50 ET | Stonehill | 5 | @ | Assumption | 4 | | | N10 | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:30 ET | Southern New Hampshire | 8 | @ | Franklin Pierce | 1 | | | N10 | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | (13) Elmira | 3 | @ | (11) Babson | 6 | | | NE | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Johnson & Wales | 1 | @ | New England College | 4 | | | NE | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | UMass Boston | 3 | @ | (1) Norwich | 3 | OT | | NE | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | (5) Hobart | 6 | @ | Southern Maine | 1 | | | NE | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Cortland | 5 | @ | Plattsburgh | 6 | OT | | SU | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Oswego | 2 | @ | Potsdam | 1 | | | SU | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Wilkes | 9 | @ | Manhattanville | 3 | | | UC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Lebanon Valley | 0 | @ | Nazareth | 3 | | | UC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | King's | 6 | @ | Neumann | 3 | | | UC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Arcadia | 1 | @ | (3) Utica | 12 | | | UC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 5:40 ET | Skidmore | 6 | @ | Anna Maria | 2 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 CT | (8) St. Norbert | 1 | @ | Augsburg | 3 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 2:00 CT | Finlandia | 3 | @ | Bethel | 4 | OT | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Saint Anselm | 3 | @ | Castleton | 2 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 CT | Wisconsin-River Falls | 2 | @ | Concordia (Minn.) | 2 | OT | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | Trine | 0 | @ | Fredonia | 4 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 CT | (6) Wisconsin-Stevens Point | 2 | @ | Gustavus Adolphus | 1 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | UMass Dartmouth | 4 | @ | Rivier | 0 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 CT | Wisconsin-Superior | 3 | @ | Saint Mary's | 4 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 8:00 CT | (7) Wisconsin-Eau Claire | 1 | @ | St. Olaf | 3 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 CT | Wisconsin-Stout | 1 | @ | St. Scholastica | 4 | | | NC | Box Score | |
| Fri. | 20211105 | 11/5/2021 | 7:00 ET | (4) Adrian | 3 | @ | US Under-18 Team | 4 | | | EX | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 2:50 ET | wnec | 1 | @ | Curry | 5 | | | CO | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 3:00 ET | Salve Regina | 2 | @ | (9) Endicott | 1 | | | CO | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 ET | Nichols | 1 | @ | (14) University of New England | 2 | | | CO | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 5:00 ET | Suffolk | 5 | @ | Wentworth | 0 | | | CO | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:30 ET | Post | 5 | @ | Assumption | 4 | | | N10 | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:30 ET | Franklin Pierce | 3 | @ | Stonehill | 5 | | | N10 | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | (5) Hobart | 2 | @ | (11) Babson | 2 | OT | | NE | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | UMass Boston | 5 | @ | New England College | 2 | | | NE | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | Johnson & Wales | 1 | @ | (1) Norwich | 8 | | | NE | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | (13) Elmira | 2 | @ | Southern Maine | 2 | OT | | NE | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 ET | Morrisville | 2 | @ | Brockport | 5 | | | SU | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 ET | Oswego | 2 | @ | Plattsburgh | 2 | OT | | SU | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 ET | Cortland | 4 | @ | Potsdam | 1 | | | SU | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | Stevenson | 3 | @ | Chatham | 1 | | | UC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 3:00 ET | King's | 5 | @ | Manhattanville | 6 | OT | | UC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | Arcadia | 1 | @ | Nazareth | 6 | | | UC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | Wilkes | 9 | @ | Neumann | 5 | | | UC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 2:00 ET | Lebanon Valley | 0 | @ | (3) Utica | 9 | | | UC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 2:00 CT | (8) St. Norbert | 1 | @ | Augsburg | 4 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 5:00 CT | Finlandia | 0 | @ | Bethel | 7 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 ET | Castleton | 2 | @ | Canton | 4 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 2:00 CT | Wisconsin-River Falls | 5 | @ | Concordia (Minn.) | 3 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 4:00 ET | Trine | 5 | @ | Fredonia | 2 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 CT | Wisconsin-Stout | 0 | @ | Gustavus Adolphus | 2 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 6:00 ET | Anna Maria | 0 | @ | Plymouth State | 2 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:40 ET | Framingham State | 2 | @ | Southern New Hampshire | 4 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 CT | Milwaukee School of Engineering | 5 | @ | (15) Saint John's | 2 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 CT | (7) Wisconsin-Eau Claire | 4 | @ | Saint Mary's | 1 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:30 CT | Wisconsin-Superior | 6 | @ | St. Olaf | 3 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 7:00 CT | (6) Wisconsin-Stevens Point | 1 | @ | St. Scholastica | 2 | | | NC | Box Score | |
| Sat. | 20211106 | 11/6/2021 | 6:00 ET | Saint Anselm | 4 | @ | Worcester State | 0 | | | NC | Box Score | |
| Sun. | 20211107 | 11/7/2021 | 3:00 CT | (12) Lake Forest | 1 | @ | Aurora | 2 | | | NC | Box Score | |
| Sun. | 20211107 | 11/7/2021 | 2:00 CT | Milwaukee School of Engineering | 4 | @ | (15) Saint John's | 4 | OT | | NC | Box Score | |
| Tue. | 20211109 | 11/9/2021 | 7:00 ET | Northland | 1 | @ | Finlandia | 3 | | | NC | Box Score | |
| Tue. | 20211109 | 11/9/2021 | 7:00 ET | Rivier | 3 | @ | Franklin Pierce | 1 | | | NC | Box Score | |
| Tue. | 20211109 | 11/9/2021 | 7:40 ET | New England College | 6 | @ | Framingham State | 0 | | | NC | Box Score | |
| Wed. | 20211110 | 11/10/2021 | 7:00 CT | Bethel | 1 | @ | Saint John's | 0 | OT | | MI | Box Score | |
| Wed. | 20211110 | 11/10/2021 | 7:00 ET | Morrisville | 0 | @ | Buffalo State | 3 | | | SU | Box Score | |
| Thu. | 20211111 | 11/11/2021 | 6:00 ET | Salem State | 0 | @ | Fitchburg State | 8 | | | MS | Box Score | |
| Thu. | 20211111 | 11/11/2021 | 7:30 ET | Framingham State | 0 | @ | UMass Dartmouth | 5 | | | MS | Box Score | |
| Thu. | 20211111 | 11/11/2021 | 6:00 ET | Westfield State | 3 | @ | Plymouth State | 3 | OT | | MS | Box Score | |
| Thu. | 20211111 | 11/11/2021 | 7:00 CT | Lawrence | 2 | @ | St. Norbert | 6 | | | NH2 | Box Score | |
| Thu. | 20211111 | 11/11/2021 | 7:00 ET | Worcester State | 4 | @ | Franklin Pierce | 3 | | | NC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | (10) University of New England | 2 | @ | (8) Endicott | 2 | OT | UNE wins SO, 1-0 | CO | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Curry | 3 | @ | Suffolk | 3 | OT | Suffolk wins SO, 1-0 | CO | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:40 ET | Post | 1 | @ | Southern New Hampshire | 3 | | | N10 | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Stonehill | 3 | @ | Saint Anselm | 3 | OT | | N10 | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | New England College | 2 | @ | Castleton | 1 | | | NE | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | (6) Babson | 6 | @ | Johnson & Wales | 0 | | | NE | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | (2) Norwich | 4 | @ | Skidmore | 4 | OT | | NE | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Southern Maine | 3 | @ | UMass Boston | 9 | | | NE | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 CT | Saint Mary's | 3 | @ | Concordia (Minn.) | 8 | | | MI | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 CT | St. Olaf | 2 | @ | St. Scholastica | 5 | | | MI | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:15 ET | (13) Aurora | 4 | @ | Finlandia | 1 | | | NH2 | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 CT | Milwaukee School of Engineering | 4 | @ | Lake Forest | 4 | OT | | NH2 | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:30 CT | (5) Adrian | 6 | @ | Marian | 2 | | | NH2 | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Concordia (Wis.) | 2 | @ | Trine | 4 | | | NH2 | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Potsdam | 0 | @ | Brockport | 3 | | | SU | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Plattsburgh | 2 | @ | (1) Geneseo | 3 | | | SU | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Cortland | 1 | @ | Oswego | 2 | | | SU | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:30 ET | Neumann | 7 | @ | Arcadia | 3 | | | UC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:30 ET | (3) Utica | 10 | @ | Chatham | 1 | | | UC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | (14) Wilkes | 5 | @ | King's | 4 | | | UC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Manhattanville | 3 | @ | Lebanon Valley | 2 | | | UC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | Nazareth | 5 | @ | Stevenson | 6 | OT | | UC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 5:40 ET | Canton | 4 | @ | Anna Maria | 2 | | | NC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 ET | (4) Hobart | 8 | @ | Buffalo State | 3 | | | NC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 CT | Bethel | 5 | @ | Northland | 1 | | | NC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 CT | Gustavus Adolphus | 0 | @ | (15) Wisconsin-Eau Claire | 2 | | | NC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:05 CT | Hamline | 2 | @ | (12) Wisconsin-River Falls | 0 | | | NC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 CT | Saint John's | 2 | @ | (11) Wisconsin-Stevens Point | 4 | | | NC | Box Score | |
| Fri. | 20211112 | 11/12/2021 | 7:00 CT | (7) Augsburg | 3 | @ | Wisconsin-Stout | 0 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 2:50 ET | Suffolk | 3 | @ | Curry | 4 | | | CO | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 8:10 ET | Salve Regina | 4 | @ | Nichols | 3 | | | CO | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 ET | (8) Endicott | 3 | @ | (10) University of New England | 1 | | | CO | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 5:00 ET | wnec | 4 | @ | Wentworth | 3 | OT | | CO | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:40 ET | Fitchburg State | 3 | @ | Framingham State | 1 | | | MS | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 5:00 ET | Plymouth State | 6 | @ | UMass Dartmouth | 3 | | | MS | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 5:35 ET | Worcester State | 6 | @ | Westfield State | 4 | | | MS | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 1:00 ET | Post | 1 | @ | Southern New Hampshire | 3 | | | N10 | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:00 ET | Stonehill | 2 | @ | Saint Anselm | 3 | | | N10 | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:00 ET | (2) Norwich | 5 | @ | Castleton | 2 | | | NE | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:30 ET | Southern Maine | 2 | @ | Johnson & Wales | 4 | | | NE | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:00 ET | New England College | 1 | @ | Skidmore | 4 | | | NE | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:00 ET | (6) Babson | 3 | @ | UMass Boston | 4 | | | NE | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 2:00 CT | Saint Mary's | 3 | @ | Concordia (Minn.) | 6 | | | MI | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 5:00 CT | St. Scholastica | 1 | @ | St. Olaf | 5 | | | MI | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:00 ET | (13) Aurora | 6 | @ | Finlandia | 3 | | | NH2 | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 8:00 CT | St. Norbert | 4 | @ | Lawrence | 3 | | | NH2 | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:30 CT | (5) Adrian | 5 | @ | Marian | 3 | | | NH2 | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 CT | Lake Forest | 4 | @ | Milwaukee School of Engineering | 3 | | | NH2 | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 5:00 ET | Concordia (Wis.) | 1 | @ | Trine | 4 | | | NH2 | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 ET | Plattsburgh | 3 | @ | Brockport | 7 | | | SU | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 ET | Potsdam | 0 | @ | (1) Geneseo | 8 | | | SU | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 ET | Fredonia | 2 | @ | Morrisville | 1 | | | SU | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 3:30 ET | Manhattanville | 5 | @ | Arcadia | 1 | | | UC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 5:30 ET | Nazareth | 2 | @ | Chatham | 5 | | | UC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 4:00 ET | Lebanon Valley | 2 | @ | Neumann | 3 | | | UC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 ET | (3) Utica | 5 | @ | Stevenson | 3 | | | UC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 3:40 ET | Canton | 0 | @ | Anna Maria | 1 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 ET | Buffalo State | 1 | @ | Elmira | 5 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 ET | Cortland | 2 | @ | (4) Hobart | 1 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 5:00 ET | Albertus Magnus | 2 | @ | King's | 3 | OT | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 2:00 ET | Hamline | 0 | @ | Northland | 1 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 CT | (7) Augsburg | 1 | @ | (15) Wisconsin-Eau Claire | 0 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:05 CT | Gustavus Adolphus | 1 | @ | (12) Wisconsin-River Falls | 3 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 CT | Bethel | 1 | @ | (11) Wisconsin-Stevens Point | 4 | | | NC | Box Score | |
| Sat. | 20211113 | 11/13/2021 | 7:00 CT | Saint John's | 3 | @ | Wisconsin-Stout | 2 | OT | | NC | Box Score | |
| Sun. | 20211114 | 11/14/2021 | 3:00 ET | Nichols | 2 | @ | Salve Regina | 3 | OT | | CO | Box Score | |
| Sun. | 20211114 | 11/14/2021 | 6:00 ET | Wentworth | 3 | @ | wnec | 4 | | | CO | Box Score | |
| Sun. | 20211114 | 11/14/2021 | 4:00 ET | (14) Wilkes | 6 | @ | Albertus Magnus | 4 | | | NC | Box Score | |
| Tue. | 20211116 | 11/16/2021 | 7:30 ET | Franklin Pierce | 3 | @ | Post | 4 | | | N10 | Box Score | |
| Tue. | 20211116 | 11/16/2021 | 7:00 CT | Wisconsin-Superior | 5 | @ | Northland | 2 | | | WI | Box Score | |
| Tue. | 20211116 | 11/16/2021 | 7:00 CT | Hamline | 2 | @ | Concordia (Minn.) | 6 | | | NC | Box Score | |
| Tue. | 20211116 | 11/16/2021 | 7:30 ET | Stonehill | 1 | @ | Framingham State | 2 | | | NC | Box Score | |
| Thu. | 20211118 | 11/18/2021 | 2:00 ET | (7) Endicott | 4 | @ | wnec | 1 | | | CO | Box Score | |
| Thu. | 20211118 | 11/18/2021 | 6:00 ET | UMass Dartmouth | 3 | @ | Fitchburg State | 4 | | | MS | Box Score | |
| Thu. | 20211118 | 11/18/2021 | 7:40 ET | Worcester State | 4 | @ | Framingham State | 0 | | | MS | Box Score | |
| Thu. | 20211118 | 11/18/2021 | 7:35 ET | Salem State | 0 | @ | Westfield State | 2 | | | MS | Box Score | |
| Thu. | 20211118 | 11/18/2021 | 7:00 CT | Saint Mary's | 2 | @ | Saint John's | 1 | | | MI | Box Score | |
| Thu. | 20211118 | 11/18/2021 | 7:00 CT | Wisconsin-Stout | 3 | @ | Northland | 1 | | | WI | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:40 ET | Curry | 6 | @ | Nichols | 2 | | | CO | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Suffolk | 3 | @ | (12) University of New England | 8 | | | CO | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Salve Regina | 6 | @ | Wentworth | 0 | | | CO | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:40 ET | Saint Anselm | 4 | @ | Southern New Hampshire | 6 | | | N10 | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Franklin Pierce | 2 | @ | Saint Michael's | 5 | | | N10 | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Castleton | 3 | @ | (8) Babson | 3 | OT | | NE | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Johnson & Wales | 1 | @ | Elmira | 5 | | | NE | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | (15) UMass Boston | 4 | @ | (6) Hobart | 8 | | | NE | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | New England College | 1 | @ | (4) Norwich | 1 | OT | | NE | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Skidmore | 2 | @ | Southern Maine | 3 | | | NE | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 CT | Gustavus Adolphus | 2 | @ | Bethel | 5 | | | MI | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 CT | Concordia (Minn.) | 1 | @ | St. Olaf | 2 | OT | | MI | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 CT | (5) Augsburg | 5 | @ | St. Scholastica | 2 | | | MI | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Trine | 2 | @ | (3) Adrian | 3 | | | NH2 | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 3:00 CT | Lake Forest | 0 | @ | (9) Aurora | 4 | | | NH2 | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 CT | Marian | 5 | @ | Concordia (Wis.) | 5 | OT | | NH2 | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:15 ET | St. Norbert | 9 | @ | Finlandia | 1 | | | NH2 | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 CT | Milwaukee School of Engineering | 3 | @ | Lawrence | 2 | | | NH2 | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Williams | 1 | @ | Colby | 0 | | | NS | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | (11) Trinity | 5 | @ | Connecticut College | 1 | | | NS | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Amherst | 1 | @ | Hamilton | 5 | | | NS | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Wesleyan | 3 | @ | Tufts | 3 | OT | | NS | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Oswego | 2 | @ | Brockport | 1 | | | SU | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Plattsburgh | 5 | @ | Buffalo State | 1 | | | SU | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Potsdam | 1 | @ | Fredonia | 6 | | | SU | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Cortland | 2 | @ | (1) Geneseo | 2 | OT | | SU | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Neumann | 5 | @ | Chatham | 5 | OT | Neumann wins SO, 2-1 | UC | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Arcadia | 4 | @ | King's | 3 | | | UC | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:30 ET | (13) Wilkes | 4 | @ | Lebanon Valley | 3 | OT | | UC | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | (2) Utica | 4 | @ | Nazareth | 1 | | | UC | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 3:00 ET | Manhattanville | 5 | @ | Stevenson | 3 | | | UC | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 CT | Wisconsin-Superior | 1 | @ | Wisconsin-Eau Claire | 5 | | | WI | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 CT | (14) Wisconsin-River Falls | 0 | @ | (10) Wisconsin-Stevens Point | 5 | | | WI | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 5:40 ET | Assumption | 3 | @ | Anna Maria | 2 | | | NC | Box Score | |
| Fri. | 20211119 | 11/19/2021 | 7:00 ET | Rivier | 1 | @ | Morrisville | 2 | | | NC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 2:50 ET | Nichols | 1 | @ | Curry | 8 | | | CO | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | wnec | 4 | @ | (7) Endicott | 5 | | | CO | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Wentworth | 3 | @ | Salve Regina | 2 | | | CO | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | (12) University of New England | 3 | @ | Suffolk | 2 | OT | | CO | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 2:00 ET | UMass Dartmouth | 4 | @ | Salem State | 3 | | | MS | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 5:35 ET | Framingham State | 4 | @ | Westfield State | 6 | | | MS | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 8:10 ET | Plymouth State | 4 | @ | Worcester State | 1 | | | MS | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Assumption | 4 | @ | Saint Michael's | 2 | | | N10 | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:30 ET | Southern New Hampshire | 3 | @ | Stonehill | 2 | | | N10 | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | Skidmore | 2 | @ | (8) Babson | 4 | | | NE | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | (15) UMass Boston | 2 | @ | Elmira | 5 | | | NE | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | Johnson & Wales | 1 | @ | (6) Hobart | 12 | | | NE | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | Castleton | 2 | @ | Southern Maine | 4 | | | NE | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 CT | St. Scholastica | 0 | @ | (5) Augsburg | 4 | | | MI | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 CT | Bethel | 2 | @ | Gustavus Adolphus | 2 | OT | Bethel wins SO, 1-0 | MI | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 CT | Saint John's | 3 | @ | Saint Mary's | 2 | OT | | MI | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 2:00 CT | Concordia (Minn.) | 3 | @ | St. Olaf | 3 | OT | St Olaf wins SO, 2-1 | MI | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | St. Norbert | 5 | @ | Finlandia | 0 | | | NH2 | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 CT | (9) Aurora | 5 | @ | Lake Forest | 2 | | | NH2 | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 CT | Concordia (Wis.) | 2 | @ | Marian | 4 | | | NH2 | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 CT | Lawrence | 2 | @ | Milwaukee School of Engineering | 1 | | | NH2 | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | (3) Adrian | 3 | @ | Trine | 2 | | | NH2 | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Williams | 1 | @ | Bowdoin | 0 | | | NS | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 3:00 ET | Wesleyan | 5 | @ | Connecticut College | 1 | | | NS | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | (11) Trinity | 6 | @ | Tufts | 4 | | | NS | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Potsdam | 1 | @ | Buffalo State | 7 | | | SU | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Brockport | 2 | @ | Cortland | 4 | | | SU | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Plattsburgh | 5 | @ | Fredonia | 2 | | | SU | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | (1) Geneseo | 6 | @ | Oswego | 1 | | | SU | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | Manhattanville | 2 | @ | Chatham | 2 | OT | Manhattanville wins SO, 2-1 | UC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Lebanon Valley | 6 | @ | King's | 4 | | | UC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Neumann | 3 | @ | Stevenson | 5 | | | UC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 5:00 ET | Arcadia | 2 | @ | (13) Wilkes | 4 | | | UC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 CT | Wisconsin-Stout | 4 | @ | Wisconsin-Eau Claire | 2 | | | WI | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:05 CT | Northland | 0 | @ | (14) Wisconsin-River Falls | 2 | | | WI | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:05 CT | (10) Wisconsin-Stevens Point | 0 | @ | Wisconsin-Superior | 3 | | | WI | Box Score | |
| Sat. | 20211120 | 11/20/2021 | | Franklin Pierce | 1 | @ | Fitchburg State | 4 | | | NC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 4:00 ET | Albertus Magnus | 4 | @ | Hamilton | 2 | | | NC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 3:00 ET | Rivier | 1 | @ | Morrisville | 1 | OT | | NC | Box Score | |
| Sat. | 20211120 | 11/20/2021 | 7:00 ET | Anna Maria | 5 | @ | Saint Anselm | 2 | | | NC | Box Score | |
| Mon. | 20211122 | 11/22/2021 | 4:00 ET | Fitchburg State | 4 | @ | Plymouth State | 5 | | | MS | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 CT | Saint John's | 5 | @ | Bethel | 1 | | | MI | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 4:00 ET | Manhattanville | 2 | @ | Albertus Magnus | 5 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 4:00 ET | Saint Michael's | 1 | @ | Amherst | 5 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | Tufts | 5 | @ | (9) Babson | 7 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | (15) Elmira | 3 | @ | Buffalo State | 4 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | Wesleyan | 0 | @ | (8) Endicott | 3 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | Framingham State | 2 | @ | Franklin Pierce | 6 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 CT | Finlandia | 0 | @ | Hamline | 2 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | Westfield State | 5 | @ | Johnson & Wales | 3 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 CT | Saint Mary's | 3 | @ | Lawrence | 3 | OT | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | Fredonia | 2 | @ | Nazareth | 2 | OT | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | LIU | 4 | @ | Saint Anselm | 0 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 2:30 ET | Chatham | 0 | @ | Trine | 3 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | Bowdoin | 1 | @ | (12) University of New England | 6 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 ET | Salem State | 4 | @ | Southern Maine | 3 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 7:00 CT | Marian | 3 | vs. | Wisconsin-Superior | 2 | | | NC | Box Score | |
| Tue. | 20211123 | 11/23/2021 | 4:40 ET | Anna Maria | 6 | @ | Worcester State | 3 | | | NC | Box Score | |
| Wed. | 20211124 | 11/24/2021 | 7:00 ET | (3) Adrian | 4 | @ | US Under-18 Team | 7 | | | EX | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 7:00 CT | (13) Wisconsin-Stevens Point | 2 | @ | Concordia (Wis.) | 1 | | | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 4:00 ET | Morrisville | 2 | @ | King's | 1 | | | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 7:00 ET | Lake Forest | 5 | @ | Manhattanville | 6 | | | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 7:00 ET | Tufts | 2 | @ | Stevenson | 6 | | | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 4:00 ET | Franklin Pierce | 2 | vs. | Arcadia | 0 | | Terry Moran Invitational | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 7:00 ET | Rivier | 2 | @ | Castleton | 7 | | Terry Moran Invitational | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 4:00 ET | (1) Geneseo | 6 | vs. | UMass Boston | 2 | | Utica Kickoff Tournament | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 7:00 ET | Amherst | 0 | @ | (2) Utica | 3 | | Utica Kickoff Tournament | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 7:00 ET | Milwaukee School of Engineering | 0 | vs. | (6) Norwich | 7 | | First Light Shootout | NC | Box Score | |
| Fri. | 20211126 | 11/26/2021 | 7:00 ET | Buffalo State | 1 | @ | US Under-18 Team | 8 | | | EX | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:00 ET | Potsdam | 0 | @ | Hamilton | 3 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 3:00 ET | Lake Forest | 3 | @ | Manhattanville | 4 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 7:00 CT | St. Olaf | 3 | @ | Marian | 5 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 5:00 ET | King's | 3 | @ | Morrisville | 5 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:00 ET | Salem State | 3 | @ | New England College | 6 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:30 ET | Tufts | 0 | @ | Stevenson | 4 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:00 ET | Southern Maine | 1 | @ | Stonehill | 5 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 5:00 ET | Buffalo State | 3 | @ | Trine | 5 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 2:00 ET | Salve Regina | 0 | @ | (10) Trinity | 4 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 2:00 ET | (3) Adrian | 7 | @ | Wesleyan | 1 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 7:00 ET | Oswego | 3 | @ | Williams | 0 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 7:00 CT | St. Norbert | 4 | @ | Wisconsin-Eau Claire | 3 | | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 7:00 CT | Concordia (Wis.) | 3 | @ | (13) Wisconsin-Stevens Point | 3 | OT | | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:00 ET | (9) Babson | 3 | @ | Bowdoin | 1 | | Bowdoin/Colby Tournament | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 1:00 ET | Wentworth | 3 | vs. | Colby | 7 | | Bowdoin/Colby Tournament | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:50 ET | Albertus Magnus | 3 | vs. | Fitchburg State | 0 | | PAL Stovepipe | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 1:40 ET | wnec | 3 | @ | Southern New Hampshire | 2 | | PAL Stovepipe | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 5:00 ET | Brockport | 2 | vs. | Connecticut College | 3 | | Skidmore Invitational | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 2:00 ET | Chatham | 3 | @ | Skidmore | 4 | OT | Skidmore Invitational | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 1:00 ET | Rivier | 4 | vs. | Arcadia | 5 | OT | Terry Moran Invitational | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:00 ET | Franklin Pierce | 1 | @ | Castleton | 3 | | Terry Moran Invitational | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:00 ET | UMass Boston | 4 | vs. | Amherst | 1 | | Utica Kickoff Tournament | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 7:00 ET | (1) Geneseo | 3 | @ | (2) Utica | 0 | | Utica Kickoff Tournament | NC | Box Score | |
| Sat. | 20211127 | 11/27/2021 | 4:00 ET | Plattsburgh | 4 | vs. | Milwaukee School of Engineering | 3 | OT | First Light Shootout | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 7:00 ET | Suffolk | 4 | @ | UMass Dartmouth | 5 | | | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 1:00 ET | (3) Adrian | 1 | @ | (10) Trinity | 0 | | | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 1:00 ET | Salve Regina | 4 | @ | Wesleyan | 1 | | | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 3:00 ET | Oswego | 3 | @ | Williams | 1 | | | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 7:00 CT | St. Norbert | 6 | @ | Wisconsin-Eau Claire | 1 | | | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 1:00 ET | Wentworth | 3 | vs. | Bowdoin | 3 | OT | Bowdoin/Colby Tournament | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 4:00 ET | (9) Babson | 5 | @ | Colby | 4 | | Bowdoin/Colby Tournament | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 1:40 ET | Fitchburg State | 3 | @ | Southern New Hampshire | 2 | | PAL Stovepipe | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 4:50 ET | Albertus Magnus | 5 | vs. | wnec | 1 | | PAL Stovepipe | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 1:00 ET | Brockport | 7 | vs. | Chatham | 1 | | Skidmore Invitational | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 4:00 ET | Connecticut College | 0 | @ | Skidmore | 1 | | Skidmore Invitational | NC | Box Score | |
| Sun. | 20211128 | 11/28/2021 | 4:30 ET | Plattsburgh | 2 | vs. | (6) Norwich | 5 | | First Light Shootout | NC | Box Score | |
| Mon. | 20211129 | 11/29/2021 | 2:30 CT | St. Olaf | 4 | @ | Marian | 5 | OT | | NC | Box Score | |
| Wed. | 20211201 | 12/1/2021 | 7:00 ET | Morrisville | 1 | @ | Cortland | 4 | | | SU | Box Score | |
| Wed. | 20211201 | 12/1/2021 | 7:00 ET | Lebanon Valley | 2 | @ | Stevenson | 5 | | | UC | Box Score | |
| Wed. | 20211201 | 12/1/2021 | 6:50 ET | UMass Dartmouth | 1 | @ | Assumption | 5 | | | NC | Box Score | |
| Thu. | 20211202 | 12/2/2021 | 6:00 ET | Framingham State | 0 | @ | Plymouth State | 4 | | | MS | Box Score | |
| Thu. | 20211202 | 12/2/2021 | 7:35 ET | Fitchburg State | 5 | @ | Westfield State | 2 | | | MS | Box Score | |
| Thu. | 20211202 | 12/2/2021 | 6:40 ET | Salem State | 2 | @ | Worcester State | 3 | | | MS | Box Score | |
| Thu. | 20211202 | 12/2/2021 | 7:00 CT | Gustavus Adolphus | 1 | @ | Saint John's | 5 | | | MI | Box Score | |
| Thu. | 20211202 | 12/2/2021 | 7:30 ET | Nazareth | 0 | @ | (11) Wilkes | 7 | | | UC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 6:50 ET | (8) Endicott | 1 | @ | (13) Curry | 2 | | | CO | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:40 ET | Wentworth | 2 | @ | Nichols | 6 | | | CO | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Salve Regina | 3 | @ | Suffolk | 0 | | | CO | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | wnec | 3 | @ | (12) University of New England | 5 | | | CO | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Saint Michael's | 2 | @ | Southern New Hampshire | 3 | | | N10 | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Elmira | 5 | @ | Castleton | 3 | | | NE | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Southern Maine | 0 | @ | (6) Norwich | 5 | | | NE | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | (5) Hobart | 4 | @ | Skidmore | 3 | OT | | NE | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 CT | (4) Augsburg | 3 | @ | Concordia (Minn.) | 1 | | | MI | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 CT | St. Scholastica | 4 | @ | Hamline | 0 | | | MI | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 CT | St. Olaf | 1 | @ | Saint Mary's | 4 | | | MI | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Milwaukee School of Engineering | 4 | @ | (2) Adrian | 9 | | | NH2 | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 4:00 CT | Finlandia | 3 | @ | Lake Forest | 6 | | | NH2 | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 CT | (7) Aurora | 6 | @ | Lawrence | 2 | | | NH2 | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 CT | Concordia (Wis.) | 1 | @ | (14) St. Norbert | 7 | | | NH2 | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Marian | 3 | @ | Trine | 6 | | | NH2 | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Tufts | 3 | @ | Middlebury | 2 | | | NS | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Amherst | 3 | @ | (10) Trinity | 2 | | | NS | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Hamilton | 3 | @ | Wesleyan | 4 | OT | | NS | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Brockport | 6 | @ | Buffalo State | 1 | | | SU | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | (1) Geneseo | 5 | @ | Fredonia | 2 | | | SU | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Potsdam | 0 | @ | Plattsburgh | 1 | | | SU | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Chatham | 6 | @ | Lebanon Valley | 2 | | | UC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Manhattanville | 1 | @ | Neumann | 3 | | | UC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | (11) Wilkes | 2 | @ | (3) Utica | 3 | | | UC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 CT | Wisconsin-Eau Claire | 3 | @ | Northland | 0 | | | WI | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 CT | (15) Wisconsin-Stevens Point | 6 | @ | Wisconsin-Stout | 3 | | | WI | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:05 CT | Wisconsin-River Falls | 1 | @ | Wisconsin-Superior | 2 | | | WI | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Oswego | 8 | @ | Canton | 2 | | | NC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 3:00 ET | Stevenson | 2 | @ | Cortland | 1 | | | NC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 8:00 ET | Albertus Magnus | 6 | @ | Post | 1 | | | NC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Anna Maria | 1 | @ | Rivier | 3 | | | NC | Box Score | |
| Fri. | 20211203 | 12/3/2021 | 7:00 ET | Johnson & Wales | 1 | @ | Stonehill | 8 | | | NC | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 3:00 ET | (13) Curry | 2 | @ | (8) Endicott | 5 | | | CO | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 8:00 ET | Suffolk | 3 | @ | Salve Regina | 4 | | | CO | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 5:00 ET | Nichols | 0 | @ | Wentworth | 3 | | | CO | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | (12) University of New England | 6 | @ | wnec | 1 | | | CO | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:00 ET | Worcester State | 3 | @ | Fitchburg State | 1 | | | MS | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:30 ET | Westfield State | 3 | @ | UMass Dartmouth | 3 | OT | | MS | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 6:00 ET | Salem State | 1 | @ | Plymouth State | 12 | | | MS | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:30 ET | Southern New Hampshire | 4 | @ | Assumption | 3 | | | N10 | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:30 ET | Post | 4 | @ | Stonehill | 2 | | | N10 | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:00 ET | (5) Hobart | 6 | @ | Castleton | 0 | | | NE | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:00 ET | (9) Babson | 6 | @ | (6) Norwich | 4 | | | NE | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:00 ET | Elmira | 2 | @ | Skidmore | 3 | | | NE | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 2:00 CT | (4) Augsburg | 2 | @ | Concordia (Minn.) | 4 | | | MI | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 CT | Saint John's | 4 | @ | Gustavus Adolphus | 1 | | | MI | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 2:00 CT | Saint Mary's | 2 | @ | St. Olaf | 1 | | | MI | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 CT | Hamline | 5 | @ | St. Scholastica | 6 | | | MI | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 3:00 ET | Milwaukee School of Engineering | 1 | @ | (2) Adrian | 6 | | | NH2 | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 CT | (14) St. Norbert | 10 | @ | Concordia (Wis.) | 2 | | | NH2 | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 1:00 CT | Finlandia | 3 | @ | Lake Forest | 10 | | | NH2 | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 5:00 CT | (7) Aurora | 1 | @ | Lawrence | 4 | | | NH2 | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 5:00 ET | Marian | 3 | @ | Trine | 4 | | | NH2 | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | Bowdoin | 1 | @ | Colby | 3 | | | NS | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:00 ET | Hamilton | 3 | @ | (10) Trinity | 2 | | | NS | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 3:00 ET | Amherst | 3 | @ | Wesleyan | 4 | | | NS | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 4:00 ET | Tufts | 4 | @ | Williams | 5 | | | NS | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | Fredonia | 2 | @ | Brockport | 4 | | | SU | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | Buffalo State | 1 | @ | (1) Geneseo | 2 | | | SU | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | Morrisville | 1 | @ | Oswego | 5 | | | SU | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 3:30 ET | Chatham | 4 | @ | Arcadia | 2 | | | UC | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | King's | 0 | @ | (3) Utica | 8 | | | UC | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:05 CT | Wisconsin-Eau Claire | 3 | @ | Wisconsin-River Falls | 4 | | | WI | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 CT | Northland | 1 | @ | (15) Wisconsin-Stevens Point | 5 | | | WI | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 CT | Wisconsin-Superior | 3 | @ | Wisconsin-Stout | 4 | | | WI | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | Cortland | 2 | @ | Manhattanville | 3 | | | NC | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | Potsdam | 5 | @ | Saint Michael's | 3 | | | NC | Box Score | |
| Sat. | 20211204 | 12/4/2021 | 7:00 ET | Anna Maria | 1 | @ | UMass Boston | 3 | | | NC | Box Score | |
| Sun. | 20211205 | 12/5/2021 | 5:00 ET | Williams | 3 | @ | Middlebury | 2 | | | NS | Box Score | |
| Sun. | 20211205 | 12/5/2021 | 5:00 ET | King's | 2 | @ | Nazareth | 5 | | | UC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 ET | Elmira | 4 | @ | Brockport | 3 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 ET | Saint Michael's | 2 | @ | Castleton | 4 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 6:30 ET | Anna Maria | 6 | @ | UMass Dartmouth | 2 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 CT | Saint Mary's | 0 | @ | Milwaukee School of Engineering | 6 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 ET | Fitchburg State | 2 | @ | New England College | 5 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 ET | (7) Norwich | 2 | @ | Plattsburgh | 2 | OT | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 ET | Connecticut College | 1 | @ | Salem State | 3 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 ET | Albertus Magnus | 3 | @ | (15) Trinity | 1 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:00 ET | Plymouth State | 4 | @ | UMass Boston | 1 | | | NC | Box Score | |
| Tue. | 20211207 | 12/7/2021 | 7:35 ET | Stonehill | 1 | @ | Westfield State | 4 | | | NC | Box Score | |
| Wed. | 20211208 | 12/8/2021 | 7:00 ET | Morrisville | 4 | @ | Potsdam | 1 | | | SU | Box Score | |
| Thu. | 20211209 | 12/9/2021 | 7:35 ET | Assumption | 2 | @ | Westfield State | 3 | OT | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:40 ET | (10) Endicott | 7 | @ | Nichols | 2 | | | CO | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | wnec | 2 | @ | Suffolk | 3 | | | CO | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Castleton | 3 | @ | Skidmore | 4 | OT | | NE | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 CT | (5) Augsburg | 5 | @ | Hamline | 1 | | | MI | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 CT | Trine | 4 | @ | (8) Aurora | 7 | | | NH2 | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Colby | 4 | @ | Tufts | 0 | | | NS | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Hamilton | 4 | @ | Williams | 1 | | | NS | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Buffalo State | 0 | @ | Cortland | 1 | | | SU | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Brockport | 1 | @ | (1) Geneseo | 3 | | | SU | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 CT | Wisconsin-River Falls | 5 | @ | Wisconsin-Stout | 4 | OT | | WI | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:05 CT | Northland | 2 | @ | Wisconsin-Superior | 2 | OT | | WI | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 5:00 ET | Neumann | 2 | @ | Albertus Magnus | 3 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Potsdam | 1 | @ | Canton | 3 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 CT | Saint John's | 5 | @ | Concordia (Wis.) | 1 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Lebanon Valley | 0 | @ | Elmira | 10 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 8:00 ET | Salve Regina | 5 | @ | Johnson & Wales | 3 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 6:00 ET | Wesleyan | 3 | @ | Plymouth State | 2 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Rivier | 3 | @ | Post | 4 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 7:00 ET | Saint Anselm | 4 | @ | Southern Maine | 6 | | | NC | Box Score | |
| Fri. | 20211210 | 12/10/2021 | 6:50 ET | Stonehill | 1 | @ | Worcester State | 2 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 ET | (12) Curry | 2 | @ | Salve Regina | 5 | | | CO | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 5:00 ET | (11) University of New England | 3 | @ | Wentworth | 1 | | | CO | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 CT | Hamline | 2 | @ | (5) Augsburg | 5 | | | MI | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 5:00 CT | Bethel | 2 | @ | St. Olaf | 5 | | | MI | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 3:00 CT | Trine | 6 | @ | (8) Aurora | 3 | | | NH2 | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 4:00 ET | Bowdoin | 3 | @ | Tufts | 2 | OT | | NS | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 ET | Fredonia | 2 | @ | Cortland | 4 | | | SU | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 ET | Plattsburgh | 4 | @ | Morrisville | 3 | OT | | SU | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 3:30 ET | Stevenson | 3 | @ | Arcadia | 0 | | | UC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 CT | Wisconsin-Superior | 5 | @ | Northland | 0 | | | WI | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 CT | (14) Wisconsin-Stevens Point | 4 | @ | Wisconsin-Eau Claire | 3 | OT | | WI | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:05 CT | Wisconsin-Stout | 1 | @ | Wisconsin-River Falls | 5 | | | WI | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 6:40 ET | Southern Maine | 2 | @ | Anna Maria | 1 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 3:00 CT | Gustavus Adolphus | 7 | @ | Concordia (Wis.) | 2 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 ET | Elmira | 4 | @ | (1) Geneseo | 3 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 6:00 ET | Franklin Pierce | 5 | @ | Johnson & Wales | 3 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 2:00 CT | Saint John's | 5 | @ | Lawrence | 0 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 7:00 ET | Oswego | 6 | @ | Nazareth | 5 | OT | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 4:00 ET | Plymouth State | 2 | @ | New England College | 3 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 2:20 ET | Neumann | 5 | @ | Rivier | 2 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 4:00 ET | (4) Hobart | 3 | @ | (15) Trinity | 4 | | | NC | Box Score | |
| Sat. | 20211211 | 12/11/2021 | 1:00 ET | (2) Adrian | 3 | vs. | (9) Wilkes | 2 | OT | | NC | Box Score | |
| Sun. | 20211212 | 12/12/2021 | 3:00 ET | Amherst | 2 | @ | Williams | 3 | OT | | NS | Box Score | |
| Tue. | 20211214 | 12/14/2021 | 7:30 ET | Saint Anselm | 3 | @ | Franklin Pierce | 5 | | | N10 | Box Score | |
| Wed. | 20211229 | 12/29/2021 | 6:00 ET | (4) Augsburg | 1 | @ | US Under-18 Team | 6 | | | EX | Box Score | |
| Wed. | 20211229 | 12/29/2021 | 1:00 ET | Rhode Island | 0 | @ | UMass Boston | 5 | | Codfish Bowl | EX | Box Score | |
| Thu. | 20211230 | 12/30/2021 | 7:00 ET | (4) Augsburg | 2 | @ | (1) Adrian | 5 | | | NC | Box Score | |
| Thu. | 20211230 | 12/30/2021 | 1:00 ET | Post | 0 | @ | UMass Boston | 7 | | Codfish Bowl | NC | Box Score | |
| Thu. | 20211230 | 12/30/2021 | 3:00 CT | St. Scholastica | 2 | vs. | (10) Aurora | 2 | OT | Superior Showdown | NC | Box Score | |
| Thu. | 20211230 | 12/30/2021 | 7:00 CT | Marian | 2 | @ | Wisconsin-Superior | 2 | OT | Superior Showdown | NC | Box Score | |
| Fri. | 20211231 | 12/31/2021 | 7:00 CT | Lake Forest | 0 | @ | Bethel | 4 | | | NC | Box Score | |
| Fri. | 20211231 | 12/31/2021 | 5:00 CT | Hamline | 4 | @ | St. Olaf | 4 | OT | | NC | Box Score | |
| Fri. | 20211231 | 12/31/2021 | 7:00 CT | Marian | 3 | vs. | (10) Aurora | 1 | | Superior Showdown | NC | Box Score | |
| Fri. | 20211231 | 12/31/2021 | 3:00 CT | St. Scholastica | 1 | @ | Wisconsin-Superior | 5 | | Superior Showdown | NC | Box Score | |
| Sat. | 20220101 | 1/1/2022 | 4:00 CT | Lake Forest | 2 | @ | Bethel | 3 | | | NC | Box Score | |
| Sat. | 20220101 | 1/1/2022 | 4:00 CT | Lawrence | 0 | @ | (12) St. Norbert | 5 | | | NC | Box Score | |
| Sat. | 20220101 | 1/1/2022 | 1:00 ET | Saint Michael's | 1 | @ | Middlebury | 5 | | Middlebury Classic | NC | Box Score | |
| Sat. | 20220101 | 1/1/2022 | 3:00 ET | Skidmore | 6 | vs. | Canton | 0 | | Pathfinder Bank Oswego | NC | Box Score | |
| Sat. | 20220101 | 1/1/2022 | 7:00 ET | (4) Augsburg | 2 | @ | Oswego | 1 | | Pathfinder Bank Oswego | NC | Box Score | |
| Sun. | 20220102 | 1/2/2022 | 4:00 ET | Milwaukee School of Engineering | 3 | vs. | (1) Adrian | 5 | | | NC | Box Score | |
| Sun. | 20220102 | 1/2/2022 | 2:30 ET | Trine | 6 | @ | Chatham | 0 | | | NC | Box Score | |
| Sun. | 20220102 | 1/2/2022 | 4:00 ET | (5) Hobart | 4 | @ | Middlebury | 1 | | Middlebury Classic | NC | Box Score | |
| Sun. | 20220102 | 1/2/2022 | 7:00 ET | Canton | 2 | @ | Oswego | 3 | | Pathfinder Bank Oswego | NC | Box Score | |
| Sun. | 20220102 | 1/2/2022 | 3:00 ET | (4) Augsburg | 2 | vs. | Skidmore | 0 | | Pathfinder Bank Oswego | NC | Box Score | |
| Mon. | 20220103 | 1/3/2022 | 3:40 ET | Neumann | 5 | @ | Assumption | 2 | | | NC | Box Score | |
| Tue. | 20220104 | 1/4/2022 | 6:10 ET | Saint Anselm | 2 | @ | Saint Michael's | 3 | | | N10 | Box Score | |
| Tue. | 20220104 | 1/4/2022 | 3:00 ET | Middlebury | 0 | @ | Bowdoin | 1 | OT | | NS | Box Score | |
| Tue. | 20220104 | 1/4/2022 | 12:30 ET | Neumann | 7 | @ | Assumption | 1 | | | NC | Box Score | |
| Tue. | 20220104 | 1/4/2022 | 4:00 ET | Post | 5 | @ | Albertus Magnus | 3 | | | NC | Box Score | |
| Tue. | 20220104 | 1/4/2022 | 7:00 ET | (9) Endicott | 0 | @ | Colby | 2 | | | NC | Box Score | |
| Tue. | 20220104 | 1/4/2022 | 1:00 ET | Rivier | 2 | @ | Cortland | 11 | | | NC | Box Score | |
| Tue. | 20220104 | 1/4/2022 | 8:20 ET | Johnson & Wales | 4 | @ | Framingham State | 2 | | | NC | Box Score | |
| Thu. | 20220106 | 1/6/2022 | 7:00 CT | Wisconsin-River Falls | 1 | @ | (4) Augsburg | 2 | | | NC | Box Score | |
| Thu. | 20220106 | 1/6/2022 | 1:00 ET | Westfield State | 3 | @ | Franklin Pierce | 2 | | | NC | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Saint Michael's | 2 | @ | Assumption | 3 | | | N10 | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | New England College | 2 | @ | (15) Elmira | 5 | | | NE | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | (8) Norwich | 3 | @ | (5) Hobart | 4 | OT | | NE | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:30 ET | Castleton | 4 | @ | Johnson & Wales | 5 | OT | | NE | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Skidmore | 0 | @ | UMass Boston | 5 | | | NE | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 CT | (11) Aurora | 1 | @ | (12) St. Norbert | 2 | | | NH2 | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Colby | 1 | @ | Hamilton | 3 | | | NS | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Middlebury | 0 | @ | Trinity | 5 | | | NS | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:30 ET | Canton | 3 | @ | Arcadia | 4 | OT | | NC | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 CT | Wisconsin-Stout | 3 | @ | Bethel | 2 | OT | | NC | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Buffalo State | 3 | @ | Chatham | 7 | | | NC | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Stevenson | 0 | @ | (2) Geneseo | 3 | | | NC | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Cortland | 7 | @ | Nazareth | 3 | | | NC | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 1:00 ET | Rivier | 3 | @ | wnec | 3 | OT | | NC | Box Score | |
| Fri. | 20220107 | 1/7/2022 | 7:00 ET | Albertus Magnus | 6 | @ | Plattsburgh | 4 | | Plattsburgh Winter Classic | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 7:00 ET | Worcester State | 2 | @ | UMass Dartmouth | 4 | | | MS | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 7:00 ET | Saint Michael's | 2 | @ | Assumption | 8 | | | N10 | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 4:00 ET | (8) Norwich | 4 | @ | (15) Elmira | 5 | | | NE | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 4:00 ET | New England College | 1 | @ | (5) Hobart | 2 | | | NE | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 5:00 ET | Skidmore | 5 | @ | Johnson & Wales | 0 | | | NE | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 4:00 ET | Castleton | 0 | @ | UMass Boston | 11 | | | NE | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 7:00 CT | Lake Forest | 2 | @ | Concordia (Wis.) | 1 | | | NH2 | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 4:00 CT | (11) Aurora | 3 | @ | (12) St. Norbert | 4 | OT | | NH2 | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 7:00 ET | Colby | 3 | @ | Amherst | 0 | | | NS | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 4:00 ET | Williams | 0 | @ | Trinity | 2 | | | NS | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 3:00 ET | Middlebury | 1 | @ | Wesleyan | 3 | | | NS | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 5:30 ET | King's | 3 | vs. | Albertus Magnus | 4 | OT | | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 3:30 ET | Canton | 4 | @ | Arcadia | 0 | | | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 7:00 CT | (13) Wisconsin-Stevens Point | 3 | @ | (4) Augsburg | 4 | OT | | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 7:00 CT | Wisconsin-River Falls | 1 | @ | Bethel | 5 | | | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 4:00 ET | Stevenson | 1 | @ | Brockport | 5 | | | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 7:00 ET | Nazareth | 6 | @ | Buffalo State | 3 | | | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 2:00 CT | Wisconsin-Superior | 4 | @ | Concordia (Minn.) | 3 | OT | | NC | Box Score | |
| Sat. | 20220108 | 1/8/2022 | 2:00 ET | (14) Curry | 2 | @ | (3) Utica | 6 | | | NC | Box Score | |
| Sun. | 20220109 | 1/9/2022 | 3:00 ET | Bowdoin | 2 | @ | Amherst | 2 | OT | | NS | Box Score | |
| Sun. | 20220109 | 1/9/2022 | 3:00 ET | Williams | 6 | @ | Wesleyan | 1 | | | NS | Box Score | |
| Sun. | 20220109 | 1/9/2022 | 4:00 CT | Northland | 0 | @ | Concordia (Minn.) | 3 | | | NC | Box Score | |
| Sun. | 20220109 | 1/9/2022 | 3:00 ET | Cortland | 0 | @ | (3) Utica | 2 | | | NC | Box Score | |
| Sun. | 20220109 | 1/9/2022 | 5:00 ET | King's | 2 | @ | Plattsburgh | 8 | | Plattsburgh Winter Classic | NC | Box Score | |
| Mon. | 20220110 | 1/10/2022 | 4:00 CT | Concordia (Wis.) | 3 | @ | Lake Forest | 2 | | | NH2 | Box Score | |
| Mon. | 20220110 | 1/10/2022 | 7:00 ET | Finlandia | 4 | @ | Trine | 6 | | | NH2 | Box Score | |
| Mon. | 20220110 | 1/10/2022 | 3:00 ET | Bowdoin | 3 | @ | Connecticut College | 2 | OT | | NS | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 4:40 ET | Saint Anselm | 1 | @ | Assumption | 2 | | | N10 | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 7:15 ET | Finlandia | 0 | @ | Trine | 5 | | | NH2 | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 3:00 ET | Amherst | 6 | @ | Middlebury | 3 | | | NS | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 3:00 ET | Connecticut College | 1 | @ | Williams | 3 | | | NS | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 7:05 CT | Wisconsin-Stout | 2 | @ | Wisconsin-River Falls | 7 | | | WI | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 5:00 ET | Morrisville | 1 | @ | Albertus Magnus | 4 | | | NC | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 5:00 ET | Tufts | 1 | @ | (12) Endicott | 6 | | | NC | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 7:00 ET | (2) Geneseo | 3 | @ | Nazareth | 2 | | | NC | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 7:00 ET | Canton | 4 | @ | Potsdam | 1 | | | NC | Box Score | |
| Tue. | 20220111 | 1/11/2022 | 5:00 ET | Cortland | 4 | @ | (7) Wilkes | 3 | | | NC | Box Score | |
| Wed. | 20220112 | 1/12/2022 | 7:00 CT | Marian | 0 | @ | Milwaukee School of Engineering | 3 | | | NH2 | Box Score | |
| Wed. | 20220112 | 1/12/2022 | 7:00 CT | Wisconsin-Eau Claire | 0 | @ | (14) Wisconsin-Stevens Point | 3 | | | WI | Box Score | |
| Wed. | 20220112 | 1/12/2022 | 7:00 ET | Canton | 7 | @ | Potsdam | 2 | | | NC | Box Score | |
| Wed. | 20220112 | 1/12/2022 | 3:00 ET | Morrisville | 1 | @ | Post | 0 | | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | Nichols | 1 | @ | (12) Endicott | 4 | | | CO | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | (15) Curry | 3 | @ | Wentworth | 2 | OT | | CO | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:30 ET | Saint Anselm | 5 | @ | Post | 1 | | | N10 | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | Skidmore | 5 | @ | Castleton | 0 | | | NE | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | (11) Norwich | 6 | @ | Johnson & Wales | 2 | | | NE | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | New England College | 2 | @ | UMass Boston | 5 | | | NE | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 CT | Bethel | 2 | @ | (4) Augsburg | 8 | | | MI | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:15 ET | (1) Adrian | 6 | @ | Finlandia | 1 | | | NH2 | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 6:00 CT | (8) St. Norbert | 7 | @ | Lake Forest | 6 | OT | | NH2 | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 CT | Marian | 1 | @ | Lawrence | 4 | | | NH2 | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 CT | Trine | 6 | @ | Milwaukee School of Engineering | 4 | | | NH2 | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | Connecticut College | 2 | @ | Amherst | 6 | | | NS | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | Buffalo State | 0 | @ | Oswego | 5 | | | SU | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | King's | 1 | @ | Chatham | 4 | | | UC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | (3) Utica | 11 | @ | Neumann | 3 | | | UC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 1:00 ET | Lebanon Valley | 1 | @ | (2) Geneseo | 8 | | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 5:30 ET | Arcadia | 2 | @ | Morrisville | 5 | | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 CT | Gustavus Adolphus | 2 | @ | Northland | 2 | OT | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 ET | Middlebury | 3 | @ | Plattsburgh | 3 | OT | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 CT | Concordia (Minn.) | 2 | @ | Wisconsin-Eau Claire | 3 | | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:35 CT | St. Olaf | 4 | @ | Wisconsin-River Falls | 2 | | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:00 CT | Saint Mary's | 3 | @ | Wisconsin-Stout | 6 | | | NC | Box Score | |
| Fri. | 20220114 | 1/14/2022 | 7:30 CT | Saint John's | 2 | @ | Wisconsin-Superior | 3 | OT | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 2:50 ET | Wentworth | 1 | @ | (15) Curry | 3 | | | CO | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 3:40 ET | (12) Endicott | 3 | @ | Nichols | 2 | | | CO | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 3:30 ET | Saint Anselm | 4 | @ | Post | 0 | | | N10 | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 ET | (6) Babson | 3 | @ | (10) Elmira | 5 | | | NE | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 ET | New England College | 11 | @ | Johnson & Wales | 0 | | | NE | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 ET | (11) Norwich | 2 | @ | UMass Boston | 1 | | | NE | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:00 CT | (4) Augsburg | 3 | @ | Bethel | 2 | | | MI | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 ET | (1) Adrian | 10 | @ | Finlandia | 0 | | | NH2 | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:00 CT | Lawrence | 5 | @ | Marian | 5 | OT | | NH2 | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 CT | Trine | 3 | @ | Milwaukee School of Engineering | 4 | OT | | NH2 | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 3:00 ET | Tufts | 3 | @ | Amherst | 5 | | | NS | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 ET | Wesleyan | 1 | @ | Bowdoin | 1 | OT | | NS | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 3:00 ET | Trinity | 2 | @ | Colby | 4 | | | NS | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 ET | (7) Wilkes | 4 | @ | Chatham | 2 | | | UC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 3:00 ET | (3) Utica | 3 | @ | Manhattanville | 2 | | | UC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 4:00 ET | Nazareth | 4 | @ | Neumann | 1 | | | UC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 2:00 ET | Lebanon Valley | 1 | @ | Brockport | 3 | | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:00 ET | Rivier | 4 | @ | Plattsburgh | 5 | OT | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:00 ET | Cortland | 1 | @ | Skidmore | 2 | | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 3:00 ET | (2) Geneseo | 3 | @ | Williams | 0 | | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:00 CT | Concordia (Minn.) | 0 | @ | Wisconsin-Eau Claire | 4 | | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:05 CT | Saint Mary's | 3 | @ | Wisconsin-River Falls | 1 | | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:00 CT | St. Olaf | 4 | @ | Wisconsin-Stout | 3 | | | NC | Box Score | |
| Sat. | 20220115 | 1/15/2022 | 7:05 CT | Gustavus Adolphus | 1 | @ | Wisconsin-Superior | 3 | | | NC | Box Score | |
| Sun. | 20220116 | 1/16/2022 | 4:00 ET | (6) Babson | 5 | @ | (5) Hobart | 3 | | | NE | Box Score | |
| Sun. | 20220116 | 1/16/2022 | 4:00 ET | Trinity | 2 | @ | Bowdoin | 1 | OT | | NS | Box Score | |
| Sun. | 20220116 | 1/16/2022 | 4:00 ET | Wesleyan | 1 | @ | Colby | 4 | | | NS | Box Score | |
| Sun. | 20220116 | 1/16/2022 | 4:00 ET | Nazareth | 3 | @ | Manhattanville | 3 | OT | Manhattanville wins SO, 2-1 | UC | Box Score | |
| Mon. | 20220117 | 1/17/2022 | 5:00 ET | Lawrence | 1 | @ | (1) Adrian | 7 | | | NH2 | Box Score | |
| Mon. | 20220117 | 1/17/2022 | 5:00 CT | (7) St. Norbert | 4 | @ | Lake Forest | 1 | | | NH2 | Box Score | |
| Mon. | 20220117 | 1/17/2022 | 7:00 ET | Potsdam | 1 | vs. | (6) Hobart | 4 | | | NC | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 6:30 ET | Plymouth State | 0 | @ | Fitchburg State | 4 | | | MS | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 7:00 ET | (5) Babson | 1 | @ | New England College | 4 | | | NE | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 2:00 ET | Lawrence | 1 | @ | (1) Adrian | 8 | | | NH2 | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 3:00 ET | Connecticut College | 2 | @ | Hamilton | 1 | | | NS | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 7:30 CT | Wisconsin-Eau Claire | 1 | @ | (13) Wisconsin-Stevens Point | 7 | | | WI | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 7:00 ET | (15) Curry | 1 | @ | Amherst | 1 | OT | | NC | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 7:00 ET | St. Olaf | 4 | @ | Gustavus Adolphus | 5 | OT | | NC | Box Score | |
| Tue. | 20220118 | 1/18/2022 | 7:00 ET | Anna Maria | 6 | @ | Johnson & Wales | 4 | | | NC | Box Score | |
| Wed. | 20220119 | 1/19/2022 | 7:00 CT | (14) Aurora | 4 | @ | Milwaukee School of Engineering | 3 | | | NC | Box Score | |
| Wed. | 20220119 | 1/19/2022 | 7:00 CT | Finlandia | 2 | @ | Northland | 4 | | | NC | Box Score | |
| Thu. | 20220120 | 1/20/2022 | 6:00 ET | Worcester State | 3 | @ | Plymouth State | 3 | OT | | MS | Box Score | |
| Thu. | 20220120 | 1/20/2022 | 7:00 ET | Fitchburg State | 6 | @ | Salem State | 3 | | | MS | Box Score | |
| Thu. | 20220120 | 1/20/2022 | 7:00 CT | St. Scholastica | 2 | @ | Saint John's | 5 | | | MI | Box Score | |
| Thu. | 20220120 | 1/20/2022 | 6:00 ET | Bowdoin | 3 | @ | Hamilton | 1 | | | NS | Box Score | |
| Thu. | 20220120 | 1/20/2022 | 7:00 CT | Northland | 3 | @ | Wisconsin-Stout | 5 | | | WI | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | (10) University of New England | 2 | @ | (15) Curry | 6 | | | CO | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:40 ET | Suffolk | 2 | @ | Nichols | 4 | | | CO | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | (12) Endicott | 7 | @ | Wentworth | 0 | | | CO | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Salve Regina | 4 | @ | wnec | 1 | | | CO | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:40 ET | Stonehill | 2 | @ | Southern New Hampshire | 6 | | | N10 | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Post | 3 | @ | Saint Michael's | 1 | | | N10 | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | UMass Boston | 5 | @ | (5) Babson | 4 | | | NE | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | (6) Hobart | 2 | @ | (8) Elmira | 0 | | | NE | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Skidmore | 5 | @ | New England College | 2 | | | NE | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Castleton | 1 | @ | (11) Norwich | 7 | | | NE | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 CT | Concordia (Minn.) | 7 | @ | Gustavus Adolphus | 1 | | | MI | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 CT | Hamline | 2 | @ | Saint Mary's | 4 | | | MI | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 CT | Saint John's | 5 | @ | St. Scholastica | 5 | OT | St Scholastica wins SO, 1-0 | MI | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Lake Forest | 4 | @ | (1) Adrian | 7 | | | NH2 | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 CT | (7) St. Norbert | 2 | @ | Marian | 1 | | | NH2 | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 CT | Concordia (Wis.) | 2 | @ | Milwaukee School of Engineering | 5 | | | NH2 | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Bowdoin | 2 | @ | Middlebury | 2 | OT | | NS | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Connecticut College | 3 | @ | Trinity | 1 | | | NS | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Tufts | 3 | @ | Wesleyan | 2 | OT | | NS | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Colby | 2 | @ | Williams | 1 | | | NS | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Fredonia | 5 | @ | Buffalo State | 1 | | | SU | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Plattsburgh | 5 | @ | Cortland | 2 | | | SU | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Potsdam | 0 | @ | Oswego | 3 | | | SU | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:30 ET | Nazareth | 7 | @ | Arcadia | 2 | | | UC | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Manhattanville | 6 | @ | King's | 2 | | | UC | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | (3) Utica | 7 | @ | Lebanon Valley | 0 | | | UC | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 5:00 ET | Neumann | 2 | @ | (9) Wilkes | 7 | | | UC | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:05 CT | (13) Wisconsin-Stevens Point | 2 | @ | Wisconsin-River Falls | 3 | | | WI | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:05 CT | Wisconsin-Eau Claire | 0 | @ | Wisconsin-Superior | 3 | | | WI | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 12:50 ET | Rivier | 2 | @ | Anna Maria | 6 | | | NC | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:00 ET | Canton | 2 | @ | Brockport | 7 | | | NC | Box Score | |
| Fri. | 20220121 | 1/21/2022 | 7:45 ET | Saint Anselm | 1 | @ | LIU | 8 | | | NC | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 5:00 ET | Wentworth | 2 | @ | (12) Endicott | 1 | OT | | CO | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 ET | wnec | 2 | @ | Salve Regina | 5 | | | CO | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 ET | Nichols | 5 | @ | Suffolk | 6 | | | CO | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Westfield State | 3 | @ | Fitchburg State | 6 | | | MS | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 2:00 ET | Plymouth State | 8 | @ | Framingham State | 3 | | | MS | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 2:00 ET | Worcester State | 0 | @ | Salem State | 5 | | | MS | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:40 ET | Franklin Pierce | 7 | @ | Southern New Hampshire | 5 | | | N10 | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Post | 1 | @ | Saint Michael's | 7 | | | N10 | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Johnson & Wales | 4 | @ | (5) Babson | 7 | | | NE | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | (8) Elmira | 5 | @ | (6) Hobart | 4 | OT | | NE | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Castleton | 3 | @ | New England College | 5 | | | NE | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Skidmore | 3 | @ | (11) Norwich | 0 | | | NE | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | UMass Boston | 1 | @ | Southern Maine | 2 | OT | | NE | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 CT | St. Olaf | 1 | @ | Bethel | 4 | | | MI | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 2:00 CT | Concordia (Minn.) | 5 | @ | Gustavus Adolphus | 1 | | | MI | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 CT | Saint Mary's | 1 | @ | Hamline | 2 | | | MI | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 3:00 ET | Lake Forest | 3 | @ | (1) Adrian | 8 | | | NH2 | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 CT | Finlandia | 1 | @ | Lawrence | 2 | | | NH2 | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 CT | Concordia (Wis.) | 1 | @ | Milwaukee School of Engineering | 5 | | | NH2 | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 CT | Marian | 1 | @ | (7) St. Norbert | 4 | | | NH2 | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Colby | 3 | @ | Middlebury | 1 | | | NS | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Tufts | 2 | @ | Trinity | 6 | | | NS | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 ET | Connecticut College | 2 | @ | Wesleyan | 1 | | | NS | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 3:00 ET | Bowdoin | 3 | @ | Williams | 2 | | | NS | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 ET | Potsdam | 3 | @ | Cortland | 1 | | | SU | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 ET | Plattsburgh | 2 | @ | Oswego | 5 | | | SU | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 3:30 ET | (3) Utica | 7 | @ | Arcadia | 0 | | | UC | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 ET | Neumann | 2 | @ | King's | 3 | | | UC | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 4:00 ET | Nazareth | 2 | @ | Lebanon Valley | 4 | | | UC | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 5:00 ET | Manhattanville | 3 | @ | (9) Wilkes | 6 | | | UC | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 CT | Wisconsin-Stout | 6 | @ | Northland | 3 | | | WI | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:05 CT | (13) Wisconsin-Stevens Point | 4 | @ | Wisconsin-River Falls | 1 | | | WI | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:05 CT | Wisconsin-Eau Claire | 4 | @ | Wisconsin-Superior | 1 | | | WI | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 7:00 ET | Brockport | 3 | @ | Canton | 1 | | | NC | Box Score | |
| Sat. | 20220122 | 1/22/2022 | 2:00 ET | Saint Anselm | 0 | @ | LIU | 7 | | | NC | Box Score | |
| Sat. | 20220122 | 1/22/2022 | | Anna Maria | 2 | @ | Stonehill | 6 | | | NC | Box Score | |
| Sun. | 20220123 | 1/23/2022 | 2:30 ET | Johnson & Wales | 0 | @ | Southern Maine | 2 | | | NE | Box Score | |
| Sun. | 20220123 | 1/23/2022 | 3:00 CT | Finlandia | 1 | @ | Lawrence | 4 | | | NH2 | Box Score | |
| Sun. | 20220123 | 1/23/2022 | 3:00 ET | Hamilton | 1 | @ | Amherst | 2 | | | NS | Box Score | |
| Mon. | 20220124 | 1/24/2022 | 8:00 ET | (12) University of New England | 3 | @ | Salve Regina | 2 | | | CO | Box Score | |
| Mon. | 20220124 | 1/24/2022 | 8:00 ET | Franklin Pierce | 4 | @ | Southern New Hampshire | 5 | | | N10 | Box Score | |
| Mon. | 20220124 | 1/24/2022 | 7:00 CT | Northland | 2 | @ | Saint John's | 5 | | | NC | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 3:30 ET | Framingham State | 2 | @ | Fitchburg State | 5 | | | MS | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 4:00 ET | UMass Dartmouth | 2 | @ | Plymouth State | 3 | OT | | MS | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 3:00 ET | Westfield State | 1 | @ | Salem State | 3 | | | MS | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 1:00 ET | Concordia (Wis.) | 2 | @ | (15) Aurora | 10 | | | NH2 | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 4:00 ET | Hamilton | 2 | @ | Middlebury | 3 | OT | | NS | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 7:00 ET | Morrisville | 3 | @ | Fredonia | 5 | | | SU | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 7:00 ET | Amherst | 2 | @ | (9) Babson | 3 | | | NC | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 7:00 ET | Southern Maine | 2 | @ | Colby | 4 | | | NC | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 7:00 ET | Albertus Magnus | 3 | @ | Connecticut College | 3 | OT | | NC | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 7:00 CT | Gustavus Adolphus | 4 | @ | St. Olaf | 2 | | | NC | Box Score | |
| Tue. | 20220125 | 1/25/2022 | 7:00 ET | Anna Maria | 3 | @ | Wesleyan | 2 | | | NC | Box Score | |
| Wed. | 20220126 | 1/26/2022 | 12:30 ET | Suffolk | 4 | @ | wnec | 4 | OT | | CO | Box Score | |
| Wed. | 20220126 | 1/26/2022 | 3:00 CT | Saint John's | 4 | @ | Hamline | 1 | | | NC | Box Score | |
| Wed. | 20220126 | 1/26/2022 | | St. Scholastica | 3 | @ | Wisconsin-Superior | 4 | | | NC | Box Score | |
| Thu. | 20220127 | 1/27/2022 | 7:00 ET | Plymouth State | 6 | @ | Salem State | 2 | | | MS | Box Score | |
| Thu. | 20220127 | 1/27/2022 | 7:35 ET | UMass Dartmouth | 4 | @ | Westfield State | 1 | | | MS | Box Score | |
| Thu. | 20220127 | 1/27/2022 | 4:40 ET | Fitchburg State | 3 | @ | Worcester State | 2 | | | MS | Box Score | |
| Thu. | 20220127 | 1/27/2022 | 7:00 CT | Wisconsin-River Falls | 1 | @ | Northland | 2 | | | WI | Box Score | |
| Thu. | 20220127 | 1/27/2022 | 7:00 ET | Canton | 2 | @ | Albertus Magnus | 5 | | | NC | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 6:50 ET | Salve Regina | 2 | @ | (10) Curry | 0 | | | CO | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | (14) Endicott | 2 | @ | Suffolk | 3 | | | CO | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | (12) University of New England | 6 | @ | Wentworth | 4 | | | CO | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:30 ET | Assumption | 3 | @ | Post | 2 | OT | | N10 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 4:00 ET | Saint Michael's | 3 | @ | Saint Anselm | 4 | OT | | N10 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Franklin Pierce | 5 | @ | Stonehill | 0 | | | N10 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Southern Maine | 4 | @ | Castleton | 3 | | | NE | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | (6) Hobart | 6 | @ | Johnson & Wales | 3 | | | NE | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | (9) Babson | 3 | @ | Skidmore | 2 | | | NE | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | (7) Elmira | 2 | @ | UMass Boston | 3 | | | NE | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | Hamline | 2 | @ | Bethel | 3 | OT | | MI | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | St. Scholastica | 1 | @ | Concordia (Minn.) | 4 | | | MI | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | (4) Augsburg | 3 | @ | St. Olaf | 2 | OT | | MI | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | Marian | 3 | @ | (15) Aurora | 7 | | | NH2 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | (1) Adrian | 11 | @ | Concordia (Wis.) | 1 | | | NH2 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:15 ET | Milwaukee School of Engineering | 3 | @ | Finlandia | 1 | | | NH2 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | Lawrence | 5 | @ | Lake Forest | 1 | | | NH2 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | Trine | 3 | @ | (5) St. Norbert | 5 | | | NH2 | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Trinity | 3 | @ | Amherst | 1 | | | NS | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Colby | 3 | @ | Bowdoin | 1 | | | NS | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Williams | 4 | @ | Connecticut College | 1 | | | NS | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Wesleyan | 3 | @ | Hamilton | 1 | | | NS | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Middlebury | 0 | @ | Tufts | 4 | | | NS | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Oswego | 5 | @ | Cortland | 3 | | | SU | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Buffalo State | 2 | @ | Fredonia | 4 | | | SU | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | (2) Geneseo | 6 | @ | Plattsburgh | 3 | | | SU | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Brockport | 2 | @ | Potsdam | 2 | OT | | SU | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Neumann | 3 | @ | Lebanon Valley | 4 | OT | | UC | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Arcadia | 3 | @ | Manhattanville | 2 | | | UC | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 5:00 ET | King's | 1 | @ | (8) Wilkes | 8 | | | UC | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 CT | Wisconsin-Eau Claire | 4 | @ | Wisconsin-Stout | 1 | | | WI | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 4:00 ET | Canton | 1 | @ | Albertus Magnus | 5 | | | NC | Box Score | |
| Fri. | 20220128 | 1/28/2022 | 7:00 ET | Rivier | 1 | @ | Southern New Hampshire | 5 | | | NC | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 1:00 ET | Saint Michael's | 2 | @ | Saint Anselm | 6 | | | N10 | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 4:00 ET | (9) Babson | 5 | @ | Castleton | 1 | | | NE | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 4:00 ET | Southern Maine | 3 | @ | Skidmore | 7 | | | NE | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 CT | St. Olaf | 1 | @ | (4) Augsburg | 7 | | | MI | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 2:00 CT | St. Scholastica | 2 | @ | Concordia (Minn.) | 4 | | | MI | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 CT | Bethel | 7 | @ | Hamline | 3 | | | MI | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 3:00 CT | Marian | 1 | @ | (15) Aurora | 2 | OT | | NH2 | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 4:00 CT | (1) Adrian | 10 | @ | Concordia (Wis.) | 0 | | | NH2 | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 4:00 ET | Milwaukee School of Engineering | 6 | @ | Finlandia | 3 | | | NH2 | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 CT | Lake Forest | 3 | @ | Lawrence | 3 | OT | | NH2 | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 4:00 CT | Trine | 5 | @ | (5) St. Norbert | 10 | | | NH2 | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 3:00 ET | Trinity | 3 | @ | Hamilton | 4 | OT | | NS | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 ET | Buffalo State | 2 | @ | Morrisville | 3 | OT | | SU | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 ET | Fredonia | 2 | @ | Oswego | 3 | | | SU | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 ET | Brockport | 3 | @ | Plattsburgh | 4 | | | SU | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 ET | (2) Geneseo | 12 | @ | Potsdam | 2 | | | SU | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 4:30 ET | Chatham | 2 | @ | Nazareth | 5 | | | UC | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 4:00 ET | Arcadia | 3 | @ | Neumann | 8 | | | UC | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 5:00 ET | Stevenson | 2 | @ | (3) Utica | 5 | | | UC | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:05 CT | Northland | 1 | @ | Wisconsin-River Falls | 3 | | | WI | Box Score | |
| Sat. | 20220129 | 1/29/2022 | 7:00 CT | Wisconsin-Eau Claire | 2 | @ | Wisconsin-Stout | 1 | OT | | WI | Box Score | |
| Sun. | 20220130 | 1/30/2022 | 6:00 ET | Nichols | 5 | @ | wnec | 4 | | | CO | Box Score | |
| Sun. | 20220130 | 1/30/2022 | 4:00 ET | (13) Norwich | 3 | @ | New England College | 2 | OT | | NE | Box Score | |
| Sun. | 20220130 | 1/30/2022 | 2:00 ET | (6) Hobart | 2 | @ | UMass Boston | 2 | OT | | NE | Box Score | |
| Sun. | 20220130 | 1/30/2022 | 3:00 ET | Wesleyan | 3 | @ | Amherst | 2 | | | NS | Box Score | |
| Sun. | 20220130 | 1/30/2022 | 4:00 ET | Connecticut College | 3 | @ | Middlebury | 2 | OT | | NS | Box Score | |
| Sun. | 20220130 | 1/30/2022 | 1:00 ET | Stevenson | 3 | @ | Nazareth | 2 | | | UC | Box Score | |
| Sun. | 20220130 | 1/30/2022 | 3:00 ET | Chatham | 0 | @ | (3) Utica | 3 | | | UC | Box Score | |
| Mon. | 20220131 | 1/31/2022 | 1:00 ET | wnec | 0 | @ | Nichols | 3 | | | CO | Box Score | |
| Mon. | 20220131 | 1/31/2022 | 7:00 ET | Salve Regina | 8 | @ | (10) University of New England | 6 | | | CO | Box Score | |
| Mon. | 20220131 | 1/31/2022 | 6:30 ET | Assumption | 6 | @ | Post | 3 | | | N10 | Box Score | |
| Mon. | 20220131 | 1/31/2022 | | Williams | 3 | @ | Tufts | 1 | | | NS | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 3:30 ET | wnec | 2 | @ | Suffolk | 4 | | | CO | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 6:00 ET | Wentworth | 0 | @ | (10) University of New England | 5 | | | CO | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 8:20 ET | Westfield State | 4 | @ | Framingham State | 2 | | | MS | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 7:30 ET | Salem State | 4 | @ | UMass Dartmouth | 1 | | | MS | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 4:00 ET | Fitchburg State | 0 | @ | Plymouth State | 3 | | | MS | Box Score | |
| Tue. | 20220201 | 2/1/2022 | | Saint Michael's | 8 | @ | Franklin Pierce | 3 | | | N10 | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 12:00 ET | Southern New Hampshire | 5 | @ | Post | 3 | | | N10 | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 7:00 ET | Saint Anselm | 4 | @ | Stonehill | 4 | OT | | N10 | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 5:30 ET | (9) Elmira | 9 | @ | Johnson & Wales | 2 | | | NE | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 5:30 ET | (15) Colby | 3 | @ | Connecticut College | 3 | OT | | NS | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 1:30 ET | Lebanon Valley | 2 | @ | Manhattanville | 2 | OT | Manhattanville wins SO, 1-0 | UC | Box Score | |
| Tue. | 20220201 | 2/1/2022 | 7:00 ET | Rivier | 4 | @ | Albertus Magnus | 7 | | | NC | Box Score | |
| Wed. | 20220202 | 2/2/2022 | 7:00 CT | Milwaukee School of Engineering | 7 | @ | Marian | 2 | | | NH2 | Box Score | |
| Wed. | 20220202 | 2/2/2022 | 7:00 ET | Brockport | 5 | @ | Morrisville | 2 | | | SU | Box Score | |
| Wed. | 20220202 | 2/2/2022 | 1:00 ET | (8) Wilkes | 3 | @ | Stevenson | 4 | OT | | UC | Box Score | |
| Wed. | 20220202 | 2/2/2022 | 7:00 CT | St. Scholastica | 4 | @ | Northland | 0 | | | NC | Box Score | |
| Wed. | 20220202 | 2/2/2022 | 7:00 CT | Wisconsin-Superior | 3 | @ | (11) Wisconsin-Stevens Point | 8 | | | NC | Box Score | |
| Wed. | 20220202 | 2/2/2022 | 3:40 ET | Assumption | 6 | @ | Worcester State | 7 | OT | | NC | Box Score | |
| Thu. | 20220203 | 2/3/2022 | 6:30 ET | Salem State | 1 | @ | Fitchburg State | 5 | | | MS | Box Score | |
| Thu. | 20220203 | 2/3/2022 | 7:30 ET | Framingham State | 3 | @ | UMass Dartmouth | 2 | OT | | MS | Box Score | |
| Thu. | 20220203 | 2/3/2022 | 6:00 ET | Westfield State | 1 | @ | Plymouth State | 3 | | | MS | Box Score | |
| Thu. | 20220203 | 2/3/2022 | 7:00 CT | Concordia (Minn.) | 4 | @ | Saint John's | 1 | | | MI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 6:50 ET | Saint Anselm | 1 | @ | Assumption | 2 | | | N10 | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Southern New Hampshire | 1 | @ | Saint Michael's | 9 | | | N10 | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Norwich | 3 | @ | (7) Babson | 2 | OT | | NE | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Skidmore | 1 | @ | (9) Elmira | 2 | | | NE | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Castleton | 2 | @ | (6) Hobart | 12 | | | NE | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | Gustavus Adolphus | 1 | @ | (4) Augsburg | 2 | | | MI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | St. Scholastica | 2 | @ | Bethel | 0 | | | MI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | Saint John's | 4 | @ | Concordia (Minn.) | 1 | | | MI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | St. Olaf | 2 | @ | Hamline | 1 | OT | | MI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | (1) Adrian | 4 | @ | (12) Aurora | 2 | | | NH2 | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | Concordia (Wis.) | 3 | @ | Lawrence | 4 | OT | | NH2 | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:15 ET | Finlandia | 0 | @ | Marian | 4 | | | NH2 | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | Milwaukee School of Engineering | 1 | @ | (5) St. Norbert | 6 | | | NH2 | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | Lake Forest | 3 | @ | Trine | 1 | | | NH2 | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Hamilton | 2 | @ | Bowdoin | 1 | OT | | NS | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Trinity | 2 | @ | Middlebury | 2 | OT | | NS | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Connecticut College | 2 | @ | Tufts | 3 | | | NS | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Wesleyan | 3 | @ | Williams | 0 | | | NS | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | (2) Geneseo | 0 | @ | Cortland | 2 | | | SU | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Brockport | 3 | @ | (13) Oswego | 7 | | | SU | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Buffalo State | 3 | @ | Plattsburgh | 4 | | | SU | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Fredonia | 2 | @ | Potsdam | 6 | | | SU | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:30 ET | (8) Wilkes | 7 | @ | Arcadia | 0 | | | UC | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | King's | 0 | @ | Lebanon Valley | 4 | | | UC | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Chatham | 6 | @ | Manhattanville | 5 | | | UC | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Stevenson | 5 | @ | Neumann | 4 | OT | | UC | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | Northland | 0 | @ | Wisconsin-Eau Claire | 2 | | | WI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:05 CT | Wisconsin-Superior | 3 | @ | Wisconsin-River Falls | 4 | | | WI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 CT | Wisconsin-Stout | 2 | @ | (11) Wisconsin-Stevens Point | 5 | | | WI | Box Score | |
| Fri. | 20220204 | 2/4/2022 | 7:00 ET | Morrisville | 1 | @ | Canton | 1 | OT | | NC | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 3:00 ET | (14) Curry | 1 | @ | Endicott | 2 | | | CO | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 5:40 ET | Wentworth | 1 | @ | Nichols | 2 | | | CO | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 ET | Salve Regina | 1 | @ | Suffolk | 1 | OT | Salve wins SO, 1-0 | CO | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:30 ET | (10) University of New England | 6 | @ | wnec | 2 | | | CO | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 12:50 ET | Fitchburg State | 4 | @ | Framingham State | 0 | | | MS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 5:00 ET | Plymouth State | 7 | @ | UMass Dartmouth | 3 | | | MS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 5:35 ET | Worcester State | 1 | @ | Westfield State | 3 | | | MS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 5:30 ET | Post | 3 | @ | Franklin Pierce | 3 | OT | | N10 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Assumption | 2 | @ | Saint Anselm | 6 | | | N10 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Southern New Hampshire | 5 | @ | Saint Michael's | 4 | OT | | N10 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | New England College | 4 | @ | (7) Babson | 5 | OT | | NE | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Castleton | 1 | @ | (9) Elmira | 4 | | | NE | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Skidmore | 4 | @ | (6) Hobart | 5 | | | NE | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Johnson & Wales | 0 | @ | UMass Boston | 5 | | | NE | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Norwich | 5 | @ | Southern Maine | 1 | | | NE | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 CT | (4) Augsburg | 6 | @ | Gustavus Adolphus | 0 | | | MI | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 5:00 CT | Hamline | 5 | @ | St. Olaf | 6 | | | MI | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 CT | Bethel | 1 | @ | St. Scholastica | 2 | | | MI | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 3:00 CT | (1) Adrian | 7 | @ | (12) Aurora | 2 | | | NH2 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 CT | Lawrence | 4 | @ | Concordia (Wis.) | 3 | | | NH2 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Finlandia | 0 | @ | Marian | 5 | | | NH2 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 CT | (5) St. Norbert | 5 | @ | Milwaukee School of Engineering | 2 | | | NH2 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 CT | Lake Forest | 1 | @ | Trine | 3 | | | NH2 | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 3:00 ET | Amherst | 5 | @ | Bowdoin | 3 | | | NS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 3:00 ET | Hamilton | 2 | @ | (15) Colby | 3 | OT | | NS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 ET | Tufts | 2 | @ | Connecticut College | 2 | OT | | NS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Wesleyan | 5 | @ | Middlebury | 2 | | | NS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 3:00 ET | Trinity | 3 | @ | Williams | 2 | | | NS | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 ET | Cortland | 3 | @ | Brockport | 3 | OT | | SU | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 ET | (13) Oswego | 2 | @ | (2) Geneseo | 4 | | | SU | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 ET | Fredonia | 1 | @ | Plattsburgh | 13 | | | SU | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 ET | Buffalo State | 1 | @ | Potsdam | 5 | | | SU | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 3:30 ET | King's | 6 | @ | Arcadia | 4 | | | UC | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 3:00 ET | Stevenson | 2 | @ | Manhattanville | 0 | | | UC | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 4:00 ET | Chatham | 2 | @ | Neumann | 3 | OT | | UC | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 2:00 ET | Nazareth | 1 | @ | (3) Utica | 7 | | | UC | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 5:00 ET | Lebanon Valley | 1 | @ | (8) Wilkes | 8 | | | UC | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 CT | Northland | 0 | @ | Wisconsin-Eau Claire | 2 | | | WI | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:00 CT | Wisconsin-Stout | 0 | @ | (11) Wisconsin-Stevens Point | 3 | | | WI | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 7:05 CT | Wisconsin-River Falls | 4 | @ | Wisconsin-Superior | 3 | | | WI | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 5:40 ET | Albertus Magnus | 3 | @ | Anna Maria | 6 | | | NC | Box Score | |
| Sat. | 20220205 | 2/5/2022 | 6:40 ET | Stonehill | 1 | @ | Rivier | 3 | | | NC | Box Score | |
| Sun. | 20220206 | 2/6/2022 | 6:50 ET | Suffolk | 2 | @ | (14) Curry | 7 | | | CO | Box Score | |
| Sun. | 20220206 | 2/6/2022 | 8:00 ET | Nichols | 1 | @ | Salve Regina | 6 | | | CO | Box Score | |
| Sun. | 20220206 | 2/6/2022 | 7:30 ET | Post | 3 | @ | Franklin Pierce | 2 | | | N10 | Box Score | |
| Sun. | 20220206 | 2/6/2022 | 1:00 ET | New England College | 7 | @ | Southern Maine | 0 | | | NE | Box Score | |
| Sun. | 20220206 | 2/6/2022 | 1:00 ET | Amherst | 1 | @ | (15) Colby | 0 | | | NS | Box Score | |
| Sun. | 20220206 | 2/6/2022 | 3:00 ET | Canton | 1 | @ | (3) Utica | 5 | | | NC | Box Score | |
| Mon. | 20220207 | 2/7/2022 | 3:50 ET | Westfield State | 0 | @ | Worcester State | 3 | | | MS | Box Score | |
| Mon. | 20220207 | 2/7/2022 | 7:00 CT | Hamline | 3 | @ | Saint John's | 8 | | | NC | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 6:00 ET | Suffolk | 0 | @ | Endicott | 3 | | | CO | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:00 ET | Curry | 1 | @ | (11) University of New England | 3 | | | CO | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 6:00 ET | wnec | 5 | @ | Wentworth | 9 | | | CO | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 6:30 ET | Fitchburg State | 5 | @ | UMass Dartmouth | 1 | | | MS | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:00 ET | Framingham State | 3 | @ | Salem State | 6 | | | MS | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:00 ET | Stonehill | 2 | @ | Saint Michael's | 3 | | | N10 | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:00 ET | UMass Boston | 6 | @ | Johnson & Wales | 1 | | | NE | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:00 ET | Southern Maine | 4 | @ | New England College | 5 | OT | | NE | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 5:00 ET | Middlebury | 2 | @ | (14) Colby | 3 | | | NS | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:00 ET | Stevenson | 2 | @ | King's | 1 | OT | | UC | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 5:40 ET | Franklin Pierce | 2 | @ | Anna Maria | 7 | | | NC | Box Score | |
| Tue. | 20220208 | 2/8/2022 | | Saint Mary's | 4 | @ | Gustavus Adolphus | 1 | | | NC | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:30 CT | Wisconsin-Eau Claire | 4 | @ | Lawrence | 4 | OT | | NC | Box Score | |
| Tue. | 20220208 | 2/8/2022 | 7:00 ET | Albertus Magnus | 1 | @ | Wesleyan | 5 | | | NC | Box Score | |
| Wed. | 20220209 | 2/9/2022 | 1:00 CT | (14) Aurora | 8 | @ | Concordia (Wis.) | 2 | | | NH2 | Box Score | |
| Wed. | 20220209 | 2/9/2022 | 7:00 ET | (11) Oswego | 4 | @ | Morrisville | 0 | | | SU | Box Score | |
| Wed. | 20220209 | 2/9/2022 | 4:00 CT | Wisconsin-Stout | 2 | @ | Hamline | 4 | | | NC | Box Score | |
| Wed. | 20220209 | 2/9/2022 | 7:00 CT | Wisconsin-Superior | 1 | @ | (10) Wisconsin-Stevens Point | 2 | OT | | NC | Box Score | |
| Thu. | 20220210 | 2/10/2022 | 6:30 ET | UMass Dartmouth | 3 | @ | Fitchburg State | 4 | OT | | MS | Box Score | |
| Thu. | 20220210 | 2/10/2022 | 7:40 ET | Worcester State | 5 | @ | Framingham State | 1 | | | MS | Box Score | |
| Thu. | 20220210 | 2/10/2022 | 7:00 ET | Westfield State | 5 | @ | Salem State | 2 | | | MS | Box Score | |
| Thu. | 20220210 | 2/10/2022 | 7:15 ET | Anna Maria | 1 | @ | Albertus Magnus | 4 | | | NC | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | wnec | 1 | @ | Endicott | 5 | | | CO | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 4:40 ET | Curry | 4 | @ | Nichols | 1 | | | CO | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 8:00 ET | Wentworth | 2 | @ | Salve Regina | 2 | OT | Salve wins SO, 1-0 | CO | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Suffolk | 2 | @ | (11) University of New England | 8 | | | CO | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 6:50 ET | Southern New Hampshire | 2 | @ | Assumption | 5 | | | N10 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 8:00 ET | Stonehill | 1 | @ | Post | 4 | | | N10 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Franklin Pierce | 1 | @ | Saint Anselm | 5 | | | N10 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 6:00 ET | Southern Maine | 1 | @ | (8) Babson | 4 | | | NE | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | UMass Boston | 2 | @ | Castleton | 2 | OT | | NE | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | (6) Hobart | 8 | @ | New England College | 5 | | | NE | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | (7) Elmira | 1 | @ | (13) Norwich | 1 | OT | | NE | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Johnson & Wales | 0 | @ | Skidmore | 6 | | | NE | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Saint Mary's | 4 | @ | (4) Augsburg | 5 | | | MI | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 CT | Hamline | 4 | @ | Gustavus Adolphus | 4 | OT | Hamline wins SO 1-0 | MI | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 CT | Saint John's | 4 | @ | St. Olaf | 2 | | | MI | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | (5) St. Norbert | 4 | @ | (1) Adrian | 8 | | | NH2 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 CT | Milwaukee School of Engineering | 3 | @ | (14) Aurora | 6 | | | NH2 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 CT | Finlandia | 3 | @ | Concordia (Wis.) | 2 | OT | | NH2 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 CT | Trine | 6 | @ | Lawrence | 2 | | | NH2 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 4:00 CT | Lake Forest | 2 | @ | Marian | 7 | | | NH2 | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Amherst | 4 | @ | Connecticut College | 1 | | | NS | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Bowdoin | 3 | @ | Trinity | 5 | | | NS | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Hamilton | 4 | @ | Tufts | 3 | OT | | NS | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | (14) Colby | 2 | @ | Wesleyan | 2 | OT | | NS | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Buffalo State | 3 | @ | Brockport | 2 | OT | | SU | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Plattsburgh | 5 | @ | Potsdam | 2 | | | SU | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Arcadia | 2 | @ | Chatham | 5 | | | UC | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | (2) Utica | 7 | @ | King's | 1 | | | UC | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Stevenson | 4 | @ | Lebanon Valley | 1 | | | UC | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Neumann | 3 | @ | Manhattanville | 4 | OT | | UC | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 4:00 ET | (9) Wilkes | 2 | @ | Nazareth | 1 | | | UC | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 CT | (10) Wisconsin-Stevens Point | 6 | @ | Northland | 2 | | | WI | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 CT | Wisconsin-River Falls | 1 | @ | Wisconsin-Eau Claire | 2 | OT | | WI | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:05 CT | Wisconsin-Stout | 6 | @ | Wisconsin-Superior | 4 | | | WI | Box Score | |
| Fri. | 20220211 | 2/11/2022 | 7:00 ET | Rivier | 1 | @ | Canton | 4 | | | NC | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 2:50 ET | (11) University of New England | 3 | @ | Curry | 2 | | | CO | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 ET | Nichols | 1 | @ | Suffolk | 2 | | | CO | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 5:00 ET | Endicott | 4 | @ | Wentworth | 1 | | | CO | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:30 ET | Salve Regina | 13 | @ | wnec | 3 | | | CO | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | UMass Dartmouth | 3 | @ | Salem State | 5 | | | MS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 5:35 ET | Framingham State | 3 | @ | Westfield State | 6 | | | MS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:30 ET | Plymouth State | 5 | @ | Worcester State | 1 | | | MS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 3:30 ET | Stonehill | 4 | @ | Post | 6 | | | N10 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:40 ET | Assumption | 3 | @ | Southern New Hampshire | 4 | | | N10 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | Franklin Pierce | 2 | @ | Saint Anselm | 3 | | | N10 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | Johnson & Wales | 3 | @ | Castleton | 4 | | | NE | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | (7) Elmira | 4 | @ | New England College | 2 | | | NE | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | (6) Hobart | 2 | @ | (13) Norwich | 0 | | | NE | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | UMass Boston | 2 | @ | Skidmore | 2 | OT | | NE | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | (8) Babson | 6 | @ | Southern Maine | 2 | | | NE | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 2:00 CT | Bethel | 5 | @ | Concordia (Minn.) | 3 | | | MI | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 CT | Gustavus Adolphus | 5 | @ | Hamline | 5 | OT | Gustavus wins SO 1-0 | MI | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 CT | St. Olaf | 1 | @ | Saint John's | 3 | | | MI | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 ET | (4) Augsburg | 7 | @ | Saint Mary's | 3 | | | MI | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 3:00 ET | (5) St. Norbert | 2 | @ | (1) Adrian | 6 | | | NH2 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 CT | Finlandia | 4 | @ | Concordia (Wis.) | 5 | | | NH2 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 CT | Marian | 6 | @ | Lake Forest | 4 | | | NH2 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 CT | Trine | 7 | @ | Lawrence | 2 | | | NH2 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 CT | (14) Aurora | 4 | @ | Milwaukee School of Engineering | 0 | | | NH2 | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 3:00 ET | Hamilton | 5 | @ | Connecticut College | 2 | | | NS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | (14) Colby | 1 | @ | Trinity | 2 | | | NS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | Amherst | 5 | @ | Tufts | 8 | | | NS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 3:00 ET | Bowdoin | 4 | @ | Wesleyan | 1 | | | NS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | Middlebury | 4 | @ | Williams | 1 | | | NS | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 ET | Brockport | 0 | @ | Fredonia | 4 | | | SU | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 ET | Cortland | 3 | @ | Morrisville | 2 | OT | | SU | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | Lebanon Valley | 2 | @ | Chatham | 3 | OT | | UC | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | Nazareth | 3 | @ | King's | 6 | | | UC | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 ET | Arcadia | 3 | @ | Stevenson | 6 | | | UC | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 ET | (2) Utica | 1 | @ | (9) Wilkes | 1 | OT | Utica wins SO 1-0 | UC | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 CT | (10) Wisconsin-Stevens Point | 7 | @ | Northland | 3 | | | WI | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 CT | Wisconsin-River Falls | 0 | @ | Wisconsin-Eau Claire | 3 | | | WI | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 7:00 CT | Wisconsin-Superior | 5 | @ | Wisconsin-Stout | 2 | | | WI | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:00 ET | Rivier | 4 | @ | Canton | 7 | | | NC | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 5:00 ET | Anna Maria | 1 | @ | Fitchburg State | 2 | | | NC | Box Score | |
| Sat. | 20220212 | 2/12/2022 | 4:30 ET | Albertus Magnus | 6 | @ | Manhattanville | 4 | | | NC | Box Score | |
| Sun. | 20220213 | 2/13/2022 | 10:45am CT | Bethel | 1 | @ | Concordia (Minn.) | 5 | | | MI | Box Score | |
| Sun. | 20220213 | 2/13/2022 | 4:00 ET | Tufts | 1 | @ | Hamilton | 6 | | | NS | Box Score | |
| Mon. | 20220214 | 2/14/2022 | 1:00 ET | Curry | 3 | @ | Salve Regina | 4 | OT | | CO | Box Score | |
| Mon. | 20220214 | 2/14/2022 | 3:40 ET | UMass Dartmouth | 3 | @ | Worcester State | 6 | | | MS | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 7:00 ET | (15) Endicott | 4 | @ | (11) University of New England | 5 | | | CO | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 8:20 ET | UMass Dartmouth | 1 | @ | Framingham State | 1 | OT | | MS | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 1:25 ET | Plymouth State | 2 | @ | Westfield State | 4 | | | MS | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 2:00 ET | Assumption | 3 | @ | Franklin Pierce | 3 | OT | | N10 | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 4:00 ET | Post | 2 | @ | Saint Anselm | 5 | | | N10 | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 5:00 ET | Middlebury | 5 | @ | Connecticut College | 3 | | | NS | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 7:00 ET | Fredonia | 3 | @ | (3) Geneseo | 2 | | | SU | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 1:00 ET | Chatham | 2 | @ | Stevenson | 3 | OT | | UC | Box Score | |
| Tue. | 20220215 | 2/15/2022 | 4:00 ET | Rivier | 3 | @ | Suffolk | 4 | OT | | NC | Box Score | |
| Wed. | 20220216 | 2/16/2022 | 3:00 ET | Southern New Hampshire | 4 | @ | Stonehill | 3 | OT | | N10 | Box Score | |
| Wed. | 20220216 | 2/16/2022 | 7:00 ET | Morrisville | 2 | @ | Plattsburgh | 4 | | | SU | Box Score | |
| Wed. | 20220216 | 2/16/2022 | 4:00 CT | (10) Wisconsin-Stevens Point | 9 | @ | Hamline | 0 | | | NC | Box Score | |
| Wed. | 20220216 | 2/16/2022 | 7:00 ET | Johnson & Wales | 1 | @ | New England College | 2 | OT | NEHC Tournament | NC | Box Score | |
| Wed. | 20220216 | 2/16/2022 | 7:00 ET | Castleton | 1 | @ | Southern Maine | 2 | OT | NEHC Tournament | NC | Box Score | |
| Thu. | 20220217 | 2/17/2022 | 6:00 ET | Framingham State | 0 | @ | Plymouth State | 7 | | | MS | Box Score | |
| Thu. | 20220217 | 2/17/2022 | 7:35 ET | Fitchburg State | 4 | @ | Westfield State | 1 | | | MS | Box Score | |
| Thu. | 20220217 | 2/17/2022 | 6:40 ET | Salem State | 1 | @ | Worcester State | 0 | | | MS | Box Score | |
| Thu. | 20220217 | 2/17/2022 | 7:00 CT | St. Scholastica | 2 | @ | Gustavus Adolphus | 1 | | | MI | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Suffolk | 3 | @ | (15) Endicott | 5 | | | CO | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Salve Regina | 3 | @ | (11) University of New England | 4 | | | CO | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Curry | 3 | @ | Wentworth | 2 | | | CO | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Nichols | 4 | @ | wnec | 1 | | | CO | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 2:00 ET | Assumption | 1 | @ | Franklin Pierce | 3 | | | N10 | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:40 ET | Saint Anselm | 2 | @ | Southern New Hampshire | 1 | OT | | N10 | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Saint Michael's | 7 | @ | Stonehill | 2 | | | N10 | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 CT | Saint John's | 1 | @ | (4) Augsburg | 5 | | | MI | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Bethel | 3 | @ | Saint Mary's | 2 | | | MI | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Middlebury | 3 | @ | Amherst | 2 | OT | | NS | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Connecticut College | 3 | @ | Bowdoin | 5 | | | NS | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Tufts | 0 | @ | Colby | 3 | | | NS | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Williams | 2 | @ | Hamilton | 2 | OT | | NS | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Trinity | 3 | @ | Wesleyan | 2 | OT | | NS | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Cortland | 4 | @ | Buffalo State | 0 | | | SU | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | (12) Oswego | 4 | @ | Fredonia | 5 | | | SU | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Arcadia | 1 | @ | Lebanon Valley | 4 | | | UC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 3:00 ET | King's | 1 | @ | Stevenson | 5 | | | UC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 5:00 ET | Chatham | 3 | @ | (9) Wilkes | 6 | | | UC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Lake Forest | 1 | @ | (1) Adrian | 2 | | NCHA Tournament | NC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 CT | Milwaukee School of Engineering | 3 | @ | (13) Aurora | 6 | | NCHA Tournament | NC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 CT | Marian | 1 | @ | (7) St. Norbert | 6 | | NCHA Tournament | NC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 CT | Northland | 1 | @ | Wisconsin-Eau Claire | 8 | | WIAC Tournament | NC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 CT | Wisconsin-Superior | 1 | @ | Wisconsin-Stout | 0 | | WIAC Tournament | NC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 5:00 ET | Rivier | 1 | vs. | Albertus Magnus | 4 | | GNAC Commissioners Cup | NC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 8:00 ET | Canton | 6 | vs. | Anna Maria | 2 | | GNAC Commissioners Cup | NC | Box Score | |
| Fri. | 20220218 | 2/18/2022 | 7:00 ET | Lawrence | 1 | @ | Trine | 4 | | NCHA Tournament Quarterfinals | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 2:50 ET | wnec | 2 | @ | Curry | 6 | | | CO | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 5:40 ET | (11) University of New England | 2 | @ | Nichols | 1 | | | CO | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 8:00 ET | (15) Endicott | 2 | @ | Salve Regina | 1 | | | CO | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | Wentworth | 1 | @ | Suffolk | 3 | | | CO | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | Worcester State | 3 | @ | Fitchburg State | 3 | OT | | MS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 3:00 ET | Westfield State | 1 | @ | UMass Dartmouth | 5 | | | MS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 6:00 ET | Salem State | 1 | @ | Plymouth State | 4 | | | MS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:30 ET | Franklin Pierce | 2 | @ | Assumption | 0 | | | N10 | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | Southern New Hampshire | 3 | @ | Saint Anselm | 2 | OT | | N10 | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:30 ET | Saint Michael's | 2 | @ | Stonehill | 4 | | | N10 | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | Saint Mary's | 4 | @ | Bethel | 0 | | | MI | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 2:00 CT | Concordia (Minn.) | 2 | @ | Hamline | 1 | | | MI | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 CT | (4) Augsburg | 2 | @ | Saint John's | 3 | | | MI | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 CT | Gustavus Adolphus | 2 | @ | St. Scholastica | 6 | | | MI | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 3:00 ET | Williams | 3 | @ | Amherst | 1 | | | NS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 3:00 ET | Tufts | 3 | @ | Bowdoin | 4 | OT | | NS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 3:00 ET | Connecticut College | 0 | @ | Colby | 4 | | | NS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 3:00 ET | Middlebury | 3 | @ | Hamilton | 2 | | | NS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | Wesleyan | 3 | @ | Trinity | 6 | | | NS | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | (3) Geneseo | 6 | @ | Brockport | 3 | | | SU | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | (12) Oswego | 3 | @ | Buffalo State | 0 | | | SU | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | Cortland | 3 | @ | Fredonia | 1 | | | SU | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | Potsdam | 6 | @ | Morrisville | 5 | | | SU | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:30 ET | Lebanon Valley | 5 | @ | Arcadia | 6 | OT | | UC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | Chatham | 5 | @ | King's | 2 | | | UC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | Neumann | 4 | @ | Nazareth | 6 | | | UC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 5:00 ET | Manhattanville | 2 | @ | (2) Utica | 6 | | | UC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | Stevenson | 1 | @ | (9) Wilkes | 3 | | | UC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | Lake Forest | 1 | @ | (1) Adrian | 3 | | NCHA Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 3:00 CT | Milwaukee School of Engineering | 7 | @ | (13) Aurora | 0 | | NCHA Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 CT | Marian | 6 | @ | (7) St. Norbert | 8 | | NCHA Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 CT | Northland | 0 | @ | Wisconsin-Eau Claire | 1 | | WIAC Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 CT | Wisconsin-Superior | 7 | @ | Wisconsin-Stout | 4 | | WIAC Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | (14) Norwich | 1 | @ | (8) Babson | 2 | OT | NEHC Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | New England College | 1 | @ | (6) Elmira | 7 | | NEHC Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | Southern Maine | 2 | @ | (5) Hobart | 5 | | NEHC Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 7:00 ET | Skidmore | 5 | @ | UMass Boston | 3 | | NEHC Tournament | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 2:30 ET | Canton | 5 | vs. | Albertus Magnus | 2 | | GNAC Commissioners Cup | NC | Box Score | |
| Sat. | 20220219 | 2/19/2022 | 4:00 ET | Lawrence | 2 | @ | Trine | 3 | OT | NCHA Tournament Quarterfinals | NC | Box Score | |
| Sun. | 20220220 | 2/20/2022 | 6:30 CT | Concordia (Minn.) | 1 | @ | Hamline | 1 | OT | Concordia wins SO, 1-0 | MI | Box Score | |
| Sun. | 20220220 | 2/20/2022 | 7:00 ET | Morrisville | 1 | @ | (3) Geneseo | 10 | | | SU | Box Score | |
| Sun. | 20220220 | 2/20/2022 | 1:00 ET | Manhattanville | 2 | @ | Nazareth | 3 | | | UC | Box Score | |
| Sun. | 20220220 | 2/20/2022 | 2:00 ET | Neumann | 1 | @ | (2) Utica | 12 | | | UC | Box Score | |
| Mon. | 20220221 | 2/21/2022 | 3:50 ET | Framingham State | 0 | @ | Worcester State | 4 | | | MS | Box Score | |
| Mon. | 20220221 | 2/21/2022 | 7:00 ET | Assumption | 5 | @ | Stonehill | 2 | | | N10 | Box Score | |
| Tue. | 20220222 | 2/22/2022 | 7:00 ET | Framingham State | 1 | @ | Salem State | 6 | | | MS | Box Score | |
| Tue. | 20220222 | 2/22/2022 | 7:00 ET | Lebanon Valley | 1 | @ | (2) Utica | 11 | | UCHC Tournament | NC | Box Score | |
| Wed. | 20220223 | 2/23/2022 | 1:00 ET | Stonehill | 1 | @ | Assumption | 3 | | | N10 | Box Score | |
| Wed. | 20220223 | 2/23/2022 | 7:00 CT | Gustavus Adolphus | 4 | @ | Hamline | 3 | | MIAC Tournament | NC | Box Score | |
| Wed. | 20220223 | 2/23/2022 | 7:00 ET | Nazareth | 2 | @ | Chatham | 4 | | UCHC Tournament | NC | Box Score | |
| Wed. | 20220223 | 2/23/2022 | 7:00 ET | Manhattanville | 4 | @ | Stevenson | 1 | | UCHC Tournament | NC | Box Score | |
| Wed. | 20220223 | 2/23/2022 | 7:00 ET | Neumann | 4 | @ | (9) Wilkes | 7 | | UCHC Tournament | NC | Box Score | |
| Fri. | 20220225 | 2/25/2022 | 7:00 ET | Connecticut College | 4 | @ | Bowdoin | 1 | | NESCAC Tournament | NC | Box Score | |
| Fri. | 20220225 | 2/25/2022 | 7:00 ET | Middlebury | 1 | @ | Tufts | 4 | | NESCAC Tournament | NC | Box Score | |
| Fri. | 20220225 | 2/25/2022 | 7:00 CT | Wisconsin-Superior | 3 | @ | (10) Wisconsin-Stevens Point | 4 | | WIAC Tournament | NC | Box Score | |
| Fri. | 20220225 | 2/25/2022 | 7:05 CT | Wisconsin-Eau Claire | 3 | @ | Wisconsin-River Falls | 2 | OT | WIAC Tournament Semifinals | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 3:00 ET | Amherst | 1 | @ | Williams | 3 | | NESCAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 ET | Fredonia | 1 | @ | Cortland | 5 | | SUNYAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 ET | Brockport | 7 | @ | Plattsburgh | 6 | OT | SUNYAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:05 ET | Trine | 2 | @ | (1) Adrian | 5 | | NCHA Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 CT | (14) Aurora | 4 | @ | (6) St. Norbert | 5 | OT | NCHA Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 CT | Gustavus Adolphus | 3 | @ | (4) Augsburg | 4 | OT | MIAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 2:00 CT | St. Olaf | 3 | @ | Concordia (Minn.) | 2 | | MIAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 CT | Bethel | 4 | @ | St. Scholastica | 3 | OT | MIAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:30 ET | Franklin Pierce | 3 | @ | Assumption | 4 | OT | Northeast-10 Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 2:15 ET | Saint Michael's | 1 | @ | Post | 3 | | Northeast-10 Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 6:00 ET | Stonehill | 5 | @ | Saint Anselm | 4 | OT | Northeast-10 Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 5:00 ET | Framingham State | 1 | @ | Fitchburg State | 0 | OT | MASCAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 5:00 ET | Westfield State | 2 | @ | UMass Dartmouth | 1 | OT | MASCAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 4:20 ET | Salem State | 4 | @ | Worcester State | 3 | | MASCAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 CT | Wisconsin-Superior | 2 | @ | (10) Wisconsin-Stevens Point | 3 | | WIAC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 ET | (8) Babson | 3 | @ | (7) Elmira | 2 | OT | NEHC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 ET | Skidmore | 3 | @ | (5) Hobart | 2 | | NEHC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 5:00 ET | Suffolk | 1 | @ | Curry | 2 | | Commonwealth Coast Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 3:00 ET | Wentworth | 1 | @ | (13) Endicott | 6 | | Commonwealth Coast Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 8:15 ET | Nichols | 3 | @ | Salve Regina | 1 | | Commonwealth Coast Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 ET | wnec | 1 | @ | (11) University of New England | 4 | | Commonwealth Coast Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:00 ET | Manhattanville | 0 | @ | (2) Utica | 4 | | UCHC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 5:00 ET | Chatham | 1 | @ | (9) Wilkes | 5 | | UCHC Tournament | NC | Box Score | |
| Sat. | 20220226 | 2/26/2022 | 7:05 CT | Wisconsin-Eau Claire | 3 | @ | Wisconsin-River Falls | 1 | | WIAC Tournament Semifinals | NC | Box Score | |
| Sun. | 20220227 | 2/27/2022 | 2:00 ET | Tufts | 1 | @ | (15) Colby | 5 | | NESCAC Tournament | NC | Box Score | |
| Sun. | 20220227 | 2/27/2022 | 1:00 ET | Connecticut College | 0 | @ | Trinity | 5 | | NESCAC Tournament | NC | Box Score | |
| Sun. | 20220227 | 2/27/2022 | 4:00 ET | Hamilton | 3 | @ | Wesleyan | 2 | | NESCAC Tournament | NC | Box Score | |
| Sun. | 20220227 | 2/27/2022 | 4:00 CT | Saint Mary's | 1 | @ | Saint John's | 5 | | MIAC Tournament | NC | Box Score | |
| Tue. | 20220301 | 3/1/2022 | 7:30 ET | Stonehill | 2 | @ | Assumption | 5 | | Northeast-10 Tournament | NC | Box Score | |
| Tue. | 20220301 | 3/1/2022 | 7:40 ET | Post | 3 | @ | Southern New Hampshire | 2 | OT | Northeast-10 Tournament | NC | Box Score | |
| Tue. | 20220301 | 3/1/2022 | 6:00 ET | Framingham State | 4 | @ | Plymouth State | 8 | | MASCAC Tournament | NC | Box Score | |
| Tue. | 20220301 | 3/1/2022 | 7:35 ET | Salem State | 4 | @ | Westfield State | 2 | | MASCAC Tournament | NC | Box Score | |
| Wed. | 20220302 | 3/2/2022 | 7:00 ET | Brockport | 1 | @ | (3) Geneseo | 3 | | SUNYAC Tournament | NC | Box Score | |
| Wed. | 20220302 | 3/2/2022 | 7:00 ET | Cortland | 0 | @ | (12) Oswego | 4 | | SUNYAC Tournament | NC | Box Score | |
| Wed. | 20220302 | 3/2/2022 | 7:00 CT | Bethel | 0 | @ | (4) Augsburg | 7 | | MIAC Tournament | NC | Box Score | |
| Wed. | 20220302 | 3/2/2022 | 7:00 ET | St. Olaf | 3 | @ | Saint John's | 1 | | MIAC Tournament | NC | Box Score | |
| Wed. | 20220302 | 3/2/2022 | 7:00 ET | Curry | 1 | @ | (13) Endicott | 2 | OT | Commonwealth Coast Tournament | NC | Box Score | |
| Wed. | 20220302 | 3/2/2022 | 7:00 ET | Nichols | 1 | @ | (11) University of New England | 4 | | Commonwealth Coast Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 4:30 ET | Hamilton | 4 | @ | (14) Colby | 6 | | NESCAC Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 1:00 ET | Williams | 0 | vs. | Trinity | 4 | | NESCAC Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 7:00 ET | (12) Oswego | 1 | @ | (3) Geneseo | 6 | | SUNYAC Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 7:00 ET | (5) St. Norbert | 3 | @ | (1) Adrian | 12 | | NCHA Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 7:00 CT | St. Olaf | 5 | @ | (4) Augsburg | 2 | | MIAC Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 6:00 ET | Post | 3 | @ | Assumption | 4 | | Northeast-10 Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 4:00 ET | Salem State | 4 | @ | Plymouth State | 8 | | MASCAC Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 7:00 CT | Wisconsin-Eau Claire | 6 | @ | (9) Wisconsin-Stevens Point | 2 | | WIAC Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 7:00 ET | Skidmore | 3 | @ | (6) Babson | 5 | | NEHC Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 7:00 ET | (13) Endicott | 2 | @ | (11) University of New England | 3 | OT | Commonwealth Coast Tournament | NC | Box Score | |
| Sat. | 20220305 | 3/5/2022 | 7:00 ET | (8) Wilkes | 4 | @ | (2) Utica | 7 | | UCHC Tournament | NC | Box Score | |
| Sun. | 20220306 | 3/6/2022 | 2:00 ET | Trinity | 4 | @ | (14) Colby | 1 | | NESCAC Tournament | NC | Box Score | |
| Sat. | 20220312 | 3/12/2022 | 7:00 ET | (14) Trinity | 0 | @ | (5) Babson | 3 | | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220312 | 3/12/2022 | 7:00 ET | (10) Elmira | 2 | @ | (7) Hobart | 4 | | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220312 | 3/12/2022 | 7:00 CT | St. Olaf | 3 | @ | (6) St. Norbert | 4 | OT | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220312 | 3/12/2022 | 7:00 ET | (15) Plymouth State | 2 | @ | (8) University of New England | 3 | 0 OT | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220319 | 3/19/2022 | 7:00 ET | (7) Hobart | 4 | @ | (1) Adrian | 7 | | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220319 | 3/19/2022 | 7:00 CT | (6) St. Norbert | 1 | @ | (4) Augsburg | 4 | | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220319 | 3/19/2022 | 7:00 ET | (5) Babson | 2 | @ | (3) Geneseo | 3 | | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220319 | 3/19/2022 | 2:00 ET | (8) University of New England | 2 | @ | (2) Utica | 0 | | NCAA3 Tournament | NC | Box Score | |
| Fri. | 20220325 | 3/25/2022 | 3:00 ET | (4) Augsburg | 1 | vs. | (1) Adrian | 5 | | NCAA3 Tournament | NC | Box Score | |
| Fri. | 20220325 | 3/25/2022 | 6:30 ET | (8) University of New England | 3 | vs. | (3) Geneseo | 8 | | NCAA3 Tournament | NC | Box Score | |
| Sat. | 20220326 | 3/26/2022 | 7:00 ET | (3) Geneseo | 2 | vs. | (1) Adrian | 5 | | NCAA3 Tournament | NC | Box Score | |
